Isoflavan

Lampe JW, Skor HE, Li S et al. Wheat bran and soy protein do not alter urinary excretion of the isoflavan equol in premonopausal women. J. Nutr. 131, 740-744, 2001. 

Kamnaing, P. et al., An isoflavan-quinone and a flavonol from Millettia laurentii. Phytochemistry, 51, 829, 1999. 

Alvarez, L. et al.. Cytotoxic isoflavans from Eysenhardtia polystachya. Journal of Natural Products, 61, 767, 1998. 

Barragan-Huerta, B.E. et al., Neocandenatone, an isoflavan-cinnamylphenol quinone methide pigment from Dalbergia congestiflora. Phytochemistry, 65, 925, 2004. 

El-Sebakhy, N.A.A. et al., Antimicrobial isoflavans from Astragalus species. Phytochemistry, 36, 1387, 1994. 

Fukai, T. et al.. Phenolic constituents of Glycyrrhiza species. 17. Three isoprenoid-substituted isoflavans, gancaonins X-Z, from Chinese folk medicine Tiexin Gancao (root xylems of Glycyrrhiza species). Natural Medicines, 48, 203, 2004. 

Kinoshita, T. et al., Isoflavan derivatives from Glycyrrhiza glabra (licorice). Heterocycles, 43, 581, 1996. 

Song, C. et al., Pterocarpans and isoflavans from Astragalus membranaceus bunge, Zhiwu Xuebao, 39, 1169, 1997. 

Subarnas, A., Oshima, Y., and Hikino, H., Isoflavans and a pterocarpan from Astragalus mongholicus, Phytochemistry, 30, 2777, 1991. 

Zeng, J.-F. et al., Three prenylated isoflavans from Maackia tenuifolia. Phytochemistry, 47, 903, 1998. 

Zeng, J.-F., Tan, C.-H., and Zhu, D.-Y., Manuifolin Q, an unusual 4-aryl-substituted isoflavan from Maackia tenuifolia, Journal of Asian Natural Products Research, 6, 45, 2004. 

Many flavonoids are known to be phytoalexins, antiviral agents, and to serve as antiinflammatory and antitumor compounds. Several isoflavones have estrogenic activity in mammals (70). (-)-Vestitol and sativan, isoflavans from Lotus species, are phytoalexins. 3R(-)-Vestitol from the resistant pasture legume Lotus pedunculatus, has been demonstrated to be a feeding deterrent... 

The difference of the substituents at C-5 is expected that European and Chinese licorices exhibit different actions in therapeutically use. For example, 5,6-disubstituted isoflavans do not showed a potency of... 

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