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Ischemic change imaging

Barber PA, Darby DG, Desmond PM, Gerraty RP, Yang Q, Li T, Jolley D, Donnan GA, Tress BM, Davis SM (1999) Identification of major ischemic change. Diffusion-weighted imaging versus computed tomography. Stroke 30 2059-2065... [Pg.145]

Kawahara H, Takeda Y, Tanaka A, Nagano O, Katayama H, Hirakawa M, Hiraki Y (2000) Does diffusion-weighted magnetic resonance imaging enable detection of early ischemic change following transient cerebral ischemia J Neurol Sci 181 73-81... [Pg.249]

Besides establishing the diagnosis of ischemic stroke, DWI also offers the capability of measuring the approximate age of infarcts. The apparent diffusion coefficient (ADC) of water, a measure of diffusion that can be derived easily from DWI images, follows a typical sequence of changes in evolving infarcts. °" ADC... [Pg.7]

A subsequent investigation (6 ) studied the resolution and sensitivity of Mn-52m as a quantitative measurement of the size and location of myocardial ischemia. Comparison between microsphere distributions and Mn-52m images taken at 1.5 cm levels revealed that an ischemic area down to the size of 2.5 cm with 50% of the normal myocardial perfusion can be seen in the positron images. In addition, a relative change of 10% or more of the normal perfusion in the ischemic area can also be observed. Large clinical studies with the Fe-52m/Mn-52m generator have recently been initiated at the National Heart and Lung and Institute, National Institutes of Health, Bethesda, Maryland ... [Pg.84]

Fig. 4.12. Mismatch concept of diffusion lesion (smaller) and perfusion deficit (larger) in human territorial brain infarction. Acute MCA territory ischemia/oligemia with a smaller, centrally located diffusion disturbance showing the relationship between infarct core, ischemic penumbra and changes in DWI and PI. DWI, diffusion-weighted imaging PI, perfusion imaging ADC, apparent diffusion coefficient ATP, high energy phosphates MCA, middle cerebral artery... Fig. 4.12. Mismatch concept of diffusion lesion (smaller) and perfusion deficit (larger) in human territorial brain infarction. Acute MCA territory ischemia/oligemia with a smaller, centrally located diffusion disturbance showing the relationship between infarct core, ischemic penumbra and changes in DWI and PI. DWI, diffusion-weighted imaging PI, perfusion imaging ADC, apparent diffusion coefficient ATP, high energy phosphates MCA, middle cerebral artery...

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