Iron oxide cores

Magnetic (iron oxide core) microspheres have been imprinted with S-pro-pranolol. The magnetism allowed the facile separation of the imprinted beads from the liquid matrix. The particles exhibited the expected affinity towards the template molecule. This technique was also proposed as a putative tool for cell sorting [81]. 

Vesicles prepared from phosphatidylglyceryl Nanometer-sized, sodium-laurate-coated Fe304 particles In the presence of vesicles, lipids adopted a bilayer configuration around the iron oxide core 792... 

CPO-coated magnetic nanoparticles with iron oxide core and polymer shell The thick polymer shell increased the stability of the nanobiocatalyst, giving no loss of activity after recycling 11 times [24]... 

Ferritin induced nanoparticle synthesis was adapted from a number of different synthetic strategies reliant upon the physical nature of ferritin. For instance, ferritin can readily exist in two stable forms (native ferritin with an intact iron oxide core or apo-ferritin lacking a mineral core) owing to the enhanced structural integrity of the protein shell. As a result, two general reaction schemes were adopted. The first route utilized the iron oxide core of native or reconstituted ferritin as a precursor to different mineral phases and types of iron nanoparticles, while the second invokes mineralization within the empty cavity of apo-ferritin. In the latter approach, the native protein must be demetallated by reductive dissolution with thioglycolic acid to yield apo-ferritin. Ultimately, apo-ferritin provides a widely applicable means to the synthesis of various nanoparticle compositions under many conditions. 

The storage and mobilization of surplus iron in eukaryotes and some prokaryotes are regulated by the iron storage protein, ferritin. Ferritin isolated from horse spleen consists of a hollow spherical shell of 24 symmetrically related protein subunits (—18 kDa per subunit) surrounding a core of inorganic hydrated iron(III) oxide 45). Phosphate may be associated with the surface of the iron oxide core in horse ferritin, but does not appear to be a critical factor for core formation in reconstituted ferritins (46). The diameter of the cavity set by the protein shell is of the order of 70-80 A, resulting in an upper limit of 4500 iron atoms (-30% wt/wt Fe) that can be stored within the molecule. 

Using the above-described experimental conditions, a stock solution of about 114 mg FCjO /mL is obtained. If desired, a further dilution with water can be executed without inducing precipitation. This is why a solution of the water-adapted, lauric acid-coated iron oxide cores is called a dilution-insensitive magnetic fluid (14) (see Note 8). 

For a 14 nm-diameter iron oxide core covered with an intact phospholipid bilayer, typically, a phospholipid /Fe O (mmol/g) ratio between 0.7 and 0.8 is calculated (see Note 17). The recip-ies to measure phosphate and iron content of the ML samples are described in the following section ... 

Due to the presence of a phospholipid bilayer coat around the iron oxide cores, the latter are quite reluctant to the solubilisation process. Therefore, it is advisable to add only the acids (37% HCl - 65% HNOj v/v 3/1), seal the tubes with a stopper to circumvent evaporation, heat till about 60°C until a clear yellow - not brown - color appears and then add the required amount of water. 

Magnetic photocatalysts were synthesized by coating titanium dioxide particles onto colloidal magnetite and nanomagnetite particles [197], The photoactivity of the prepared coated particles was lower than that of single-phase Ti02 and was found to decrease with an increase in the heat treatment. These observations were explained in terms of an unfavorable heterojunction between the titanium dioxide and the iron oxide core, leading to an increase in electron-hole recombination. 

There are a large number of inorganic NPs that can be potentially used in the biomedical field among them, metallic NPs (MNPs) such as gold, cobalt, iron oxide, core-shell silica/gold and more recently silver have been studied. In addition, during the last few years, biological applications of carbon nanoparticles... 

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