Iron and its Sources

Haemoglobin-derived haem iron has multiple pro-inflammatory effects resulting from its ability to initiate decomposition of lipid hydroperoxides from PUFAs. In 

1962 Pathak and Stratton, 1968) and in skin homogenates (Nishi et al., 1991 Ogura et al., 1991), although direct measurement of such in vivo events is technically very difficult. As can be seen from the discussion so far, most authors have opted for indirect assessment of ROS activity by looking at defence enzyme levels ex vivo or in vivo, which are easier to measure. 

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