Intrauterine foreign bodies

It has been suggested that a nonspecific foreign body reaction is the unifying principle in the mechanism of intrauterine foreign body action. In primates, the mechanism of action remains unknown a number of subsequent biological changes which have been described are secondary... 

Top left unused Lippes loop D top right Lippes loop D after 5 yrs of intrauterine service and bottom glycoproteinaceous coatings extracted with distilled water from plastic (left) and steel (right) intrauterine foreign bodies that were in place 5 yrs. Points with small symbols were not included in straight-line fit. 

In Figure 4 are presented other typical IR spectra that characterize the equilibrium surface deposits on intrauterine foreign bodies of different materials and configurations with different periods of intrauterine exposure. Time of exposure varied from 4.5 yrs (the upper left-hand spectrum of the coating on a stainless-steel ring) to only 1.5 yrs (the lower right-hand spectrum of the coating on a Lippes loop) all exposures occurred... 

Figure 3. Internal reflection IR spectra characterizing the equilibrium surface layers coating plastic (top) and steel (bottom) intrauterine foreign bodies, each...

Figure 4. Internal reflection IR spectra illustrating the similarity of the coating acquired in utero on the surfaces of various intrauterine foreign bodies that were in place for various lengths of time...

Effect of Adsorbed Protein on New lUDs. A new, promising improvement in contraceptive technology involves the installation of intrauterine foreign bodies loaded with certain steroids (24) which can diffuse through the wall of these devices in microquantities at slow and constant rates. Also, the addition of copper to the lUD surface greatly improves contraceptive effectiveness (25, 26). Since these devices introduce new materials to the intrauterine environment, they create the need for more detailed understanding of the effect of that enviroment on the surface... 

Parr, E., Intrauterine Foreign Bodies A Toxoid Effect of Leukocyte Ex-... 

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