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Intranasal peptide delivery enhancement

Sulfobutylether P-cyclodextrin can form noncovalent complexes with many types of compounds including small organic molecules, peptides, and proteins. It can also enhance their solubility and stability in water. The first application of sulfobutylether P-cyclodextrin was in injectable preparations it can also be used in oral solid and liquid dosage forms, and ophthalmic, inhalation, and intranasal formulations. Sulfobutylether P-cyclodextrin can function as an osmotic agent and/or a solubilizer for controlled-release delivery, and has antimicrobial preservative properties when present at sufficient concentrations. [Pg.754]

See other pages where Intranasal peptide delivery enhancement is mentioned: [Pg.301]    [Pg.304]    [Pg.232]    [Pg.357]    [Pg.301]    [Pg.270]    [Pg.344]    [Pg.353]    [Pg.622]    [Pg.1356]    [Pg.1611]    [Pg.2701]    [Pg.791]    [Pg.93]    [Pg.1710]    [Pg.1711]   
See also in sourсe #XX -- [ Pg.301 , Pg.302 , Pg.303 , Pg.304 , Pg.305 , Pg.306 , Pg.307 ]



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