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Integrons, antibiotic resistance gene

Tennstedt T, Szczepanowski R, Braun S et al (2003) Occurrence of integron-associated resistance gene cassettes located on antibiotic resistance plasmids isolated from a waste water treatment plant. EEMS Microbiol Ecol 45(3) 239-252... [Pg.208]

Rowe-Magnus DA, Mazel D (2002) The role of integrons in antibiotic resistance gene capture. Int J Med Microbiol 292(2) 115-125... [Pg.211]

Figure 2 Integrons, transposons, and R-plasmids often collect multiple antibiotic resistance genes. As a result, selection of one resistance mechanism coselects for resistance to additional resistance genes. The scheme shows a typical arrangement for an integron with associated integrase-encoding gene (int), a promoter to drive gene transcription (P), and antibiotic resistance elements (A- ). Figure 2 Integrons, transposons, and R-plasmids often collect multiple antibiotic resistance genes. As a result, selection of one resistance mechanism coselects for resistance to additional resistance genes. The scheme shows a typical arrangement for an integron with associated integrase-encoding gene (int), a promoter to drive gene transcription (P), and antibiotic resistance elements (A- ).
Over 4 decades, between 1960 and 2000, the development of new antibiotics used well characterized basic structures for partial synthetic modifications, primarily to overcome resistance by increasing the pharmacodynamic properties and, secondarily, to improve the pharmacokinetic profile of older compounds. However, bacteria rapidly responded by acquiring additional genetic alterations either as mutations or by accumulating resistance genes as part of mobile genetic elements ( integrons) on transferable resistance plasmids. [Pg.103]

Chen B, Zheng W, Yu Y et al (2011) Class 1 integrons, selected virulence genes, and antibiotic resistance in Escherichia coli isolates from the Minjiang River, Fujian Province, China. Appl Environ Microbiol 77(1) 148-155... [Pg.211]

See other pages where Integrons, antibiotic resistance gene is mentioned: [Pg.638]    [Pg.181]    [Pg.187]    [Pg.188]    [Pg.200]    [Pg.315]    [Pg.638]    [Pg.201]    [Pg.86]    [Pg.86]    [Pg.94]    [Pg.3174]    [Pg.230]    [Pg.474]    [Pg.709]    [Pg.701]    [Pg.201]   
See also in sourсe #XX -- [ Pg.230 ]



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