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Mobile genetic element

Over 4 decades, between 1960 and 2000, the development of new antibiotics used well characterized basic structures for partial synthetic modifications, primarily to overcome resistance by increasing the pharmacodynamic properties and, secondarily, to improve the pharmacokinetic profile of older compounds. However, bacteria rapidly responded by acquiring additional genetic alterations either as mutations or by accumulating resistance genes as part of mobile genetic elements ( integrons) on transferable resistance plasmids. [Pg.103]

Nojiri H, Shintani M, Omori T (2004) Divergence of mobile genetic elements involved in the distribution of xenobiotic-catabolic capacity. Appl Microbiol Biotechnol 64 154-174... [Pg.38]

Top EM, Springael D (2003) The role of mobile genetic elements in baderial adaptation to xenobiotic organic compounds Curr Opin Biotechnol 14 262-269... [Pg.38]

Springael D, Top EM (2004) Horizontal gene transfer and microbial adaptation to xenobio-tics new types of mobile genetic elements and lessons from ecological studies. Trends Microbiol 12 53-58... [Pg.38]

Top EM, Springael D, Boon N (2002) Catabolic mobile genetic elements and their potential use in bioremediation of polluted soils and waters. FEMS Microbiol Ecol 42 199-208... [Pg.38]

Sherratt, D. J., ed. (1995) Mobile Genetic Elements, Oxford Univ. Press, New York... [Pg.1598]

Shapiro, J. A., Mobile Genetic Elements. New York Academic Press, 1983. [Pg.675]

The control of mating type in yeast illustrates a specialized role of mobile or transposable genetic elements in which mobile elements hop from one site to another. Mobile genetic elements are commonly found in both prokaryotes and eukaryotes, but most of them show little site specificity. Indeed, their almost random insertion behavior has led to the proposal that their major function in most cases is to promote evolutionary change. [Pg.806]

Mobile genetic element. A segment of the genome that can move as a unit from one location on the genome to another, without any requirement for sequence homology. [Pg.914]

Table 2.4. Mobile genetic elements and other repetitive sequences in platyhelminth genomes. [Pg.44]

Brindley, P.J., Laha, T., McManus, D.P. and Loukas, A. (2003) Mobile genetic elements colonizing the genomes of metazoan parasites. Trends in Parasitology 19, 79-87. [Pg.69]

See other pages where Mobile genetic element is mentioned: [Pg.312]    [Pg.235]    [Pg.3]    [Pg.3]    [Pg.27]    [Pg.38]    [Pg.311]    [Pg.160]    [Pg.299]    [Pg.195]    [Pg.200]    [Pg.41]    [Pg.128]    [Pg.60]    [Pg.166]    [Pg.527]    [Pg.176]    [Pg.203]    [Pg.1024]    [Pg.70]    [Pg.46]    [Pg.145]    [Pg.151]    [Pg.164]    [Pg.164]    [Pg.236]    [Pg.256]    [Pg.238]    [Pg.605]    [Pg.299]    [Pg.299]    [Pg.85]    [Pg.86]    [Pg.87]    [Pg.89]   
See also in sourсe #XX -- [ Pg.26 ]

See also in sourсe #XX -- [ Pg.150 ]



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