Integrated drug discovery

Gardner SP. Ontologies and semantic data integration Drug Discovery Today 2005 10 1001-7. 

ChemOvation Ltd., founded in 1998, focuses on providing an integrated drug discovery support service via collaborative programs, and the manufacture of innovative compound libraries. Apart from that, their range of services includes chemistry development, automated parallel synthesis, scale-up, process development, and screening. 

There is intense economic pressure on the pharmaceutical industry by those who pay for its products to make the development of drugs more efficient and thereby reduce or at least contain costs. Industry executives ignore this clamor at their own peril. A widely embraced strategy to improve productivity is to integrate drug discovery and development by bringing company researchers from basic, preclini-... 

Borchardt, R.T., Integrating drug discovery and development. AAPS Newsmagazine, 2001. 4(5) 5. 

P.A. Keifer, The NMR toolkit for compound characterization, Integrated Drug Discovery Technologies, 485 541, 2002. 

Dewey, T.M., Nieuwlandt, D., Tarasow, T. Integrated drug discovery in a test tube. Current Drug Discovery July 21-25 (2002).. 

Discovery Cycle an integrated drug discovery process or cycle (Fig. 7). In this... 

Treherne, J.M. 2006. Exploiting high-throughput ion channel screening technologies in integrated drug discovery. Curr. Pharm. Des. 12, 397 -06. 

Mei, Houng-Yau, Anthony W. Czarnik, and ebrary Inc. Integrated Drug Discovery Technologies. New York Marcel Dekker, 2002. 

Figure 2.4 Integrated drug discovery and development (adapted from Taylor, 1993)...

Figure 8.12 Ensemble s integrated drug discovery platform based on DPC . Reprinted with permission from Ensemble Discovery.

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