Inorganic sunscreens

Albini A, ed. Drugs. Photochemistry and Photostability. Cambridge Royal Society of Chemistry, 1998. 

Albini A, Fasani E, eds. Photochemistry of drags. In Nalwa HS (ed.), Handbook of Photochemistry and Photobiology, Vol. 2. Organic Photochemistry. Stevenson Ranch American Scientific Publishers, 2003 143-93. 

Cosa G. Photodegradation and photosensitization in pharmaceutical products Assessing drug phototoxicity. Pure Appl Chem 2004 76 263-75. 

Verma K, Agrawal N, Misra RB, Farooq M, Hans RK. Phototoxicity assessment of drugs and cosmetic products using E. coli. Toxicology in Vitro 2008 22 249-53. 

Hans RK, Agrawal N, Verma K, Misra RB, Ray RS, Farooq M. Assessment of the phototoxic potential of cosmetic products. Food and Chemical 2008 46 1653-8. 

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Dunford, R., Salinaro, A., Cai, L., Serpone, N., Horikoshi, S., Hidaka, H. and Knowland, J. (1997) Chemical oxidation and DNA damage catalysed by inorganic sunscreen ingredients. FEBS Letters, 418, 87-90. 

Therefore inorganic sunscreens commonly used in cosmetic industry should be carefully tested for their photoactivity and phototoxicity. Sunscreens based on titanium and zinc oxides should contain additional antioxidants, eg a-tocopherol or j5-carotene. Even more efficient protection against unwanted ROSs can be achieved by a smart titanium dioxide modification that would block its photocatalytic activity. Recently Lee et al. described a hydrophobic multicomponent polymer coating for nanocrystalline Ti02 containing natural antioxidants extracted from grape seeds... 

In the case of the inorganic sunscreens, fine particles of titanium oxide (Ti02) and zinc oxide (ZnO) are effective and are popularly used in the eosmeties [41]. Although titanium oxide is the most popular inorganic sunscreen agent, it is known... 

Villalobos-Hernandez, J.R. and C.C. Miiller-Goymann. Physical stability, centrifugation tests, and entrapment efficiency studies of carnauba wax-decyl oleate nanoparticles used for the dispersion of inorganic sunscreens in aqueous media. Eur J Pharm Biopharm, 63 (2006) 115-127. 

Ceria also exhibits optical properties suitable for potential applications. Ceria has characteristics ideal for use as a broad-spectrum inorganic sunscreen in personal care products it is quite transparent to visible light, but has excellent ultraviolet absorption ability. Thin ftims of ceria have a high refractive index n = 2.05), and dc... 

Uses Emollient, moisturizer, moisture binder, gloss aid, thickener, softener in colored cosmetics, shampoos, conditioners, bath and shower preps. gloss aid in lipsticks thickener, emulsifier in liq. makeup pigment dispersant in color cosmetic applies, such as lip glosses, and in inorganic sunscreens Features Compat. with water... 

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