Influence qualities

Adopt a procedure for measuring and monitoring results such as SPC to detect future changes that could influence quality... 

Handling techniques at harvest which influence quality... 

Test procedures should include all parameters that are susceptible to change during storage and that are likely to influence quality, safety, and/or efficacy. These include, as appropriate, physical, chemical, biological, and microbiological characteristics, and for drug products, loss of preservative and functionality. Validated, stability-indicating methods should be used. 

Physiological accessibility of the essential amino acids also influences quality. Alkali-treated proteins have been shown to have reduced digestibility in vitro (7,49,76) and in vivo (49, 62) and to produce symptoms of dietary inadequacy such as poor growth, hair loss, and diarrhea (34, 54, 75). 

During the collection or harvesting phase, skilled labor can be an important factor that influences quality of the harvest of wild plants. Deliberate adulteration most frequently occurs with expensive natural substances or natural substances in short supply. Mechanical devices may be more economical in the collection of some plants but may be of little use when only particular parts of another plant are desired. Cultivated plants ensure a more reliable source of the desired plant with less risk of substitution. Environmental conditions (temperature, rainfall, day length and sunlight, altitude, atmosphere, and soil) can dramatically affect quality, concentration, and presence of active constituents in plants. The age of the plant can also be an important determinant of the quality of active constituents in a crude drug. 

ASHP s Center on Managed Care Pharmacy monitors, analyzes, and reports on trends in managed care pharmacy, creates specialized programming at ASHP s national meetings, conducts conferences and workshops, conducts surveys, monitors and influences quality-related measures, and coordinates networking opportunities. 

Micronutrients are elements such as Boron, Zinc, Copper, Cobalt, Iron, Magnesium etc. which are required in trace amounts. The addition of extra trace elements has no effect on plant growth but a deficiency of any or all of these can cause serious disturbance of plant growth, leading to a loss of active chemical. Since plants can be cultivated in areas with different soils of varying fertility, it follows that the site of cultivation could influence quality, indicating again the need for assays for chemical content. 

The physical and chemical properties of dry beans are primary factors in determining subsequent final product quality. Dry bean seed structure is comprised of a seed coat and an embryonic cotyledon. Structurally, seed coat, cell walls, middle lamella and other cellular membranes greatly influence performance. Further, chemical components (carbohydrates, proteins, phytate, polyphenols and lignin) directly influence quality. 

The testing should cover those features susceptible to change during storage and likely to influence quality, safety and/or efficacy. Stability information should cover as necessary the physical, chemical and microbiological test characteristics. Validated stability-indicating testing methods must be applied. The need for the extent of replication will depend on the results of validation studies. 

Factors influencing quality in grapes are variety, climate, soil, and vineyard management. 

Several products containing terpenes are more highly refined which influences quality and quantities of terpenes in these products e.g. in oil of turpentine or in resin components. The quantity of monoterpenes is essentially influenced by the composition of the raw materials, e.g. d-limonene dominates in agmmen oils as citrus oil products. ... 

The management system standards in these families state requirements for what the organization must do to manage processes influencing quality (ISO 9000) or the processes influencing the impact of the organization s activities on the environment (ISO 14000). In both cases, the philosophy is that these requirements are generic. 

Hotchkiss JH. Food-packaging interactions influencing quality and safety. Food Addit Contam 1997 14 601-607. 

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