Indol glucosinolates

McDannell R and McLean AEM. 1988. Chemical and biological properties of indole glucosinolates (glucobrassicins) a review. Food Chem Toxicol 26 59—70. 

BAK, S., TAX, F.E., FELDMANN, K.A., GALBRAITH, D.W., FEYEREISEN, R., CYP83B1, A cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis, Plant Cell, 2001,13,101-111. 

Besides its role as an intermediate in indole glucosinolate biosynthesis, it has been suggested that IAOX is involved in IAA biosynthesis.40,41 This has been supported by the biochemical characterization of LAOX-metabolizing enzymes that convert IAOX to either indole-3-acetaldehyde,42,43 indole-3-acetonitrile,42,44 or... 

When the expression of CYP79B2 was driven by the 35S promoter, a 4-fold increase in indole glucosinolates was observed for approximately 20% of the transgenic lines, whose appearance also resembled that of wild-type plants.13 The majority (approximately 80%) of the 35S CYP79B2 lines exhibited dwarfism, did not develop inflorescences, and, therefore, did not produce seeds. A possible explanation for this phenotype could be that the LAOX produced by CYP79B2 was partly channeled into production of the plant hormone IAA, which would disturb the growth and development of the plants. 

When the expression of CYP79B2 was driven by the 35S promoter, a 4-fold increase in indole glucosinolates was observed for approximately 20% of the transgenic lines, whose appearance also resembled that of wild-type plants.13 The... 

MIKKELSEN, M.D., HANSEN, C.H., WITTSTOCK, U., HALKIER, B.A., Cytochrome P450 CYP79B2 from Arabidopsis catalyzes the conversion of tryptophan to indole-3-acetaldoxime, a precursor of indole glucosinolates and indole-3-acetic acid, J. Biol. Chem., 2000, 275,33712-33717. 

Bender J Celenza JL (2009) Indolic glucosinolates at the crossroads of tryptophan metabolism. Phytochem Rev 8 25-37... 

Agerbirk N, Vos M, Kim JH, Jander G (2009) Indole glucosinolate breakdown and its biological effects. Phytochem Rev 8 101-120... 

Indolic glucosinolates have been reported in Balis marilinta, but a test of this species did not give a reaction with DragendorfT s reagent. 

Indole glucosinolates have attracted attention, as they appear to be precursors of anticancer factors (81M11 83MI2), and their potential toxic-... 

Brader, G, Tas, E., Palva, E.T. Jasmonate-dependent induction of indole glucosinolates in Arabidopsis by culture filtrates of the non-specific pathogen Erwinia caratovora. Plant Physiol 2001 126 849-860. 

CHEVOLLEAU, S., GASC, N., ROLLIN, P., TULLIEZ, J., Enzymatic, chemical, and thermal breakdown of H-3-labeled glucobrassicin, the parent indole glucosinolate., J. Agric. Food Chem., 1997, 45, 4290-4296. 

AGERBIRK, N., OLSEN, C.E, SORENSEN, H., Initial and final products, nitriles, and ascorbigens produced in myrosinase-catalyzed hydrolysis of indole glucosinolates., J. Agric. Food Chem., 1998,46, 1563-1571. 

When plants undergo various stresses, certain secondary metabolites, including defense compounds, accumulate. Several secondary metabolites such as terpenoid indole alkaloids, indole glucosinolate, nicotine alkaloids, and polyamines are known to accumulate through the induction of biosynthetic genes by jasmonates.898-900 MeJA also induces genes involved in the formation of tryptophan derivatives, terpenoid indole alkaloids.901 These compounds are known to be involved in defense response to pathogen attack as phytoalexins. 

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