Indinavir American ginseng

No changes in plasma levels or clearance rate of indinavir, as compared to baseline, were observed in healthy volunteers orally administered indinavir (800 mg 3 times daily for 3 days, then 1 g 3 times daily for 2 weeks) after two weeks of coadministration of 3g American ginseng capsules daily (Andrade et al. 2008). 

Human studies have shown a lack of interaction between American ginseng and indinavir or zidovudine (Andrade et al. 2008 Lee et al. 2008). 

Andrade, A.S., C. Hendrix, T.L. Parsons, et al. 2008. Pharmacokinetic and metabolic effects of American ginseng Panax quinque/dius) in healthy volunteers receiving the HIV protease inhibitor indinavir. BMC Complement. Altem. Med. 8 50. 

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