Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

CoMSIA (comparative molecular similarity index analysis) is a recent development from CoMFA and does not suffer from the alignment problem. It has been used to model hERG potassium channel inhibition by drugs [59] and the toxicity of phenylsulfonyl carboxylates [60], organophosphates [61], and polybrominated diphenyl ethers [62], with results comparable to those from CoMFA. [Pg.481]

See other pages where INDEX potassium channel is mentioned: [Pg.406] [Pg.67] [Pg.58] [Pg.586] [Pg.191] [Pg.775] [Pg.103] [Pg.70] [Pg.276]

See also in sourсe #XX -- [ Pg.237 , Pg.238 , Pg.239 ]