INDEX macrocyclic structure

Porphyrins - Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the a-positions by four methine groups to form a macrocyclic structure (porphyrin is designated porphine in Chemical Abstracts indexes). [5]... 

We have deposited also thin films of a modified fumrot by functionalizing the macrocycle with NOj group, as it is seen in Fig. 10. The optical absorption spectra of modified in this way fumrot with mono and di-substitution are shown in Fig. 11. Later we will show that such modification, which doesn t alter significantly the absorption band, influence significantly the structural order and the value of refractive index through the influence of the substitution on the molecular packing in solid state. 

Formula Index Structure Substitutents (Numbers indicate position on macrocycle) (%) References... 

As another example of Stille chemistry directed towards macrocycles, 1,6-naphthyridines (106) were constructed from active acyclic precursors 105 (Scheme ll.ll) based on the crystal structure, which revealed a proximity between substituents on the naphthyridine and phenyl rings. The antiviral activity of the 14- and 15-membered cyclic compounds proved to be 25-to 150-fold higher than the linear counterpart against human cytomegalovirus (HCMV) strains with one analogue 450-fold better versus ganciclovir-resistant isolates with a selectivity index of 3000. 

---