INDEX definition

Full-Text Index for the Submission. You should provide an index of the full text and the Document Information fields of all items in the submission. The index is generated in PDF by using Acrobat Catalog. Name the index definition file indindex.pdx. You should place all associated index hies in a folder named indindex. Place the indindex.pdx definition hie and the indindex folder in the IND main folder. Associate the XXXX indtoc.pdf Ie with the index hie so that, whenever the TOC hie is opened, the associated index is automatically added to the available index list. This will facilitate the use of the search function in Adobe Acrobat. The function enables a reviewer to enter a specihc word and search the document for that word s location throughout the documents covered by the indices loaded at the time. The indindex folder and hie do not have numerical prehxes because they are intended to be cumulative. Index information should be updated each time an amendment is submitted to the IND. 

Full-Text Index You should provide an index of the full text and the Document Information fields of all documents in this folder. You should name the index definition file pharmtox.pdx. You should place all associated index files... 

This index quantifies how much of the servo-DIS is covered by the AIS. If its value is less than one, it indicates a need to increase the available ranges of some of the inputs. For linear systems, both these operability index definitions give the same value. However, there will be some differences between the calculated values for nonlinear systems. 

DAEs can be classified by their index. We defined in Sec. 2.6.3 the index of a linear DAE by the index of nilpotency of the corresponding matrix pencil. For the general, nonlinear case there are many different index definitions, which might lead to different classifications in special cases. Here we will introduce the so-called perturbation index which allows to categorize the equations by means of their sensitivity under perturbations, [HLR89]. 

---