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Increased Risk of Toxicity in Cancer Patients with Gilberts Syndrome

3 Increased Risk of Toxicity in Cancer Patients with Gilbert s Syndrome [Pg.294]

SN-38 glucuronidation is catalyzed by the polymorphic UDP-glucuronosyltransfer-ase 1A1 (UGT1A1) enzyme, which is responsible for bilirubin glucuronidation [Pg.294]

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Cancer risk

Cancer toxicity

Cancers patients with

Gilbert

Gilbert syndrome

In toxicity

Patients risks

Risks increased

Risks of cancer

Toxic syndromes

Toxicity increased

Toxicity increases