Improper project evaluation

A method is discussed here, which is based on OSBL conditions. This method can have a profound influence on evaluating project economics and thus determining the project selection. Improper project evaluation could lead to bad investment decisions bad projects are selected and good projects are discarded, which, regrettably, is common in energy optimization evaluations. To avoid the bad investment decisions and determine the true benefits for energy-saving projects, the effects on incremental steam, power, boiler feed water (BFW), and fuel balances must be assessed. A practical example is provided the next to illustrate how this method is applied. 

Students will observe and evaluate the proper and improper ways to handle chemical materials used in art projects. 

The selection of improved variants from a library of genotypes is crucial because it guides the development of a protein toward a certain functionality. In other words, the precise definition and implementation of the selection criteria comprise the most important steps in any directed evolution project When, for example, improper library generation techniques are chosen, a directed evolution project will run slower and less efficiently. In the extreme, there will be no progress at all. However, if improper selection processes are chosen, the directed evolution project will run in the wrong direction generating useless protein phenotypes. Careful consideration and evaluation of available selection processes is therefore key to successful directed evolution projects. 

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