Implant fixation

L3. Lind, M., Growth factor stimulation of bone healing. Effects on osteoblasts, osteomies, and implants fixation. Acta Orthoped. Scand. 283, 2-37 (1998). 

Soballe, K. (1993) Hydroxyapatite ceramic coating for bone implant fixation. Mechanical and histological studies in dogs. Acta Orthop. Scand., 64 (Suppl. 255), 58 pp. 

Figure 7.82 shows that without a hydroxyapatite coating no solid implant fixation could be achieved. Instead, a layer of connective tissue of varying thickness... 

Kuroda, S., Virdi, A.S., Li, P., Healy, ICE., and Sumner, D.R. (2004) A low-temperature biomimetic calcium phosphate surface enhances early implant fixation in a... 

The ceramics such as hydroxyapatite (HAp) or titanium oxide have been used to make the metallic implants more osteogenic. Endoprostheses coated with HAp are widely used to improve implant fixation to the bone. The different methods of coating of the porous and non porous titanium implants with the ceramic layers. A electrochemical deposition method was used to obtain HAp layer on the pure highly porous titanium scaffolds (total porosity - 75 %) fabricated by Powder... 

Pilliar RM (2005) Cementless implant fixation-toward improved reliability. Orthop Clin North Am 36(1) 113-119... 

Friedman, R.F., Black, J., Galante, J.O. et al., 1994. Current concepts in orthopaedic biomaterials and implant fixation. In Instructional Course Lectures, J.M. Schafer (Ed.), pp. 233-255. The American Academy of Orthopaedic Surgeons. 

Key words orthopaedic, implant fixation, fracture healing, viscosupplementation, bone morphogenic protein. 

Other materials used to achieve implant fixation such as porous metal and calcium ceramics are commercially bonded to implant surfaces, not injected. With better understanding of bioactive peptides, the future may bring the use of signaling molecules to augment biologic implant fixation. Bioactive peptides could be commercially bonded to the substrate surface or injected in liquid or gel form at the time of implantation. 

The composition and structure of scaffolds used in tissue engineering are aitical for successful implantation into the host s injury site. An accelerated stable implant fixation with reduced risk of infection significantly reduces the physical suffering, psychological impact, and health care cost of patients. Biochemical methods for immobilization and/or delivery of proteins, enzymes, or peptides at the tissue-implant interface have been employed at devices that can induce controlled and rapid healing. 

Implant Fixation with Pink Dental Acrylic Cement (1958-1966)... 

Thomas KA, Cook SD. An evaluation of variables influencing implant fixation by direct bone apposition. J Biomed Mater Res 1985 19 875-901. 

The balance between these tissue varieties is controlled by the action of chemical mediators which issue instructions for the amount of bone and soft tissue to be formed as an appropriate healing response. This delicate balance can easily be disturbed inadvertently and may cause the undesirable end-result of an interfacial soft tissue embedment of the implant or, in the case of fracture healing, formation of a pseudoarthrosis. The discussion in this section will focus on various modes of implant fixation, such as cementation, ingrowth and osseointegration (Figure 3.1). 

Bone cement, a two component acrylic, is frequently used for implant fixation in the cases of hip and knee arthroplasties. Bone cement is toxic with localized as well as general adverse tissue reactions [2], Therefore, the good long-term results reported with cemented arthroplasties seem to be quite puzzling. However, it must be understood that the strength of... 

Kienapfel H, Sprey C, Wilke A, Griss P (1999), Implant fixation by bone ingrowth , J Arthroplasty, 14, 355-368. 

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