Immunoglobulin content

Spray-dried plasma is a palatable source of digestible amino acids for newly weaned piglets. Its immunoglobulin content enhances gut health. 

Suitable affinity columns of this type have been designed for use with HPLC and this offers an extremely rapid method of analyzing or purifying antibodies. However, the method will detect any mammalian immunoglobulin which means that the immunoglobulin content of the serum used in the growth medium may interfere with analysis. 

Immunosera and human immunoglobulins depend for their protective effects on their content of antibodies derived, in the case of immunosera, flxm immunized animals and, in the case of immunoglobulins, flxm humans who have been immunized or who have high antibody titres consequent upon prior infection. This form of immunity, known as passive immunity, is achieved immediately but is limited in its duration to the time that protective levels of antibodies remain in the circulation see also Chapter 16. 

Figure 3. Compositional oscillations observed in the human chromosome 22 fragment (23Mbp, NT 011520.8) after low-pass filtering at scale 2 — 160kbp (see Fig. 2). (a) GC content, (b) Total skew S — Sta + See [Efi- (2)]. The red (blue) portions of the profiles correspond to the location of sense (antisense) genes that have the same (opposite) orientation than the sequence. The location of the immunoglobulin locus is shown in pink. See color insert.

A number of other proteins are now known to exhibit heterogeneity with respect to their carbohydrate content these include pig pancreatic ribonuclease,9 rabbit19 and human109-238 -yG immunoglobulin, ceruloplasmin,239 2-acetamido-2-deoxy-/3-D-glucosidase,240 and the blood-group substances from ovarian cysts.145,241... 

There are five classes of antibodies or immunoglobulins.59 60 Tire first three, IgG, IgM, and IgA, are quantitatively the most significant, but IgD and IgE are also important. For example, the content of IgE is elevated in allergic persons. The basic structure of all of the immunoglobulins is that of a quasi-symmetric dimer composed of a pair of light chains and a pair of heavy chains whose lengths vary among the different... 

Proteins present in whole egg, yolk, and albumen (egg white) are excellent sources of nutrients, and they possess valuable functional properties. Shell eggs consist of 8-11% shell, 56-61% albumen, and 27-32% yolk. The solid content of albumen is about 11-13%, depending on the strain and on the age of the hens, and the solid content of yolk is about 52-53.5%. Albumen solids contain mainly protein, whereas lipids are the major constituents of egg yolk (92). Yolk can be separated by centrifugation into sedimented granules and a supernatant, plasma. The granules contain the major part of the yolk proteins. The main proteins in albumen and yolk are ovalbumin, ovotransferin, lysozyme, ovomucoid, ovomucin, and immunoglobulin Y (93). 

Tonegawa, S., Hozumi, N., Matthyssens, G Schuller, R. (1976). Somatic changes in the content and context of immunoglobulin genes. Cold Spring Harbor Symp. Quant. Biol. 41,877-889. 

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