Immune system natural immunity

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HIV is also good at evading the innate immunity system. Natural killer cells attempt to attack the virus, but HIV binds a particular cell protein, called cyclophilin, to its capsid, which blocks the antiviral agent known as restriction factor-1. Another of HIV s proteins blocks the viral inhibitor called CEM-15, which normally disrupts the viral life cycle. 

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Advances in immunology during the last part of the twentieth century have continued at a rapid rate and cytokines and immune cells having specific markers continue to be defined. A number of natural and synthetic immunotherapeutic agents have been discovered that can modulate components of the normal or aberrant immune system, through stimulation or suppression. However, most of these substances also have inherent adverse side effects. 

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