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Immune system development changes impairing

Intense research has revealed much about the molecular mechanisms involved in tumour development but much less is known about the metabolic changes in cancer. Nonetheless, most deaths from cancer are caused not directly by the tumour but by infections due to an immune system that has been impaired by metabolic disturbances in the whole... [Pg.496]

Reproductive toxicity to 2,3,7,8-TCDD has been demonstrated in animals. "" The effects include pre- and postimplantation losses in females, morphologic and functional changes in male and female reproductive organs, and hormonal imbalance in both sexes. A number of developmental effects have been observed in animals acutely exposed to 2,3,7,8-TCDD by the oral route. Effects observed in offspring of animals include cleft palate, kidney anomalies, immune system damage (thymic atrophy and immunosuppression), impaired development of the reproductive system, decreased growth, and fetal/newborn mortality. [Pg.136]

See other pages where Immune system development changes impairing is mentioned: [Pg.328]    [Pg.387]    [Pg.372]    [Pg.829]    [Pg.23]    [Pg.198]    [Pg.37]    [Pg.2529]    [Pg.381]    [Pg.31]    [Pg.177]    [Pg.286]    [Pg.182]    [Pg.265]    [Pg.212]    [Pg.1136]    [Pg.332]    [Pg.346]    [Pg.534]   
See also in sourсe #XX -- [ Pg.54 ]



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Immune development

Immune system, developing

Immune systems

Impaired

Impairment

System Development

Systems change

Systems developed

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