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Immune Interferons Gene biological activity

The immune interferon gene has been isolated, sequenced, and expressed.20 One approach for studying the biological activity of immune interferon is to change the amino acid... [Pg.63]

Myxomatosis is associated with general immunosuppression of the host and thus MV was a prime candidate to encode immune evasion molecules. Initial work identified the MV M-T7 gene encoding a 37 kDa glycoprotein that is abundantly secreted from infected cells. The M-T7 ORF showed significant similarity to the extracellular binding domain of human and mouse interferon-y receptors (IFN-yRs), and was shown to bind to and inhibit the biological activity of rabbit IFN-y in a species specific manner. ... [Pg.15]


See other pages where Immune Interferons Gene biological activity is mentioned: [Pg.746]    [Pg.172]    [Pg.38]    [Pg.2]    [Pg.346]    [Pg.172]    [Pg.22]    [Pg.298]    [Pg.86]    [Pg.941]   
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