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Immune complex reactions pathophysiology

The pathophysiology of immune complex reactions occurs in several stages formation of immune complexes in antigen excess, deposition of complexes in tissue, activation of complement followed by attraction at the site of plynuclear neutrophils, and liberation in tissue of proteolytic lysosomal enzymes and inflammatory cationic proteins. The importance of concomitant increase in vascular permeability for the deposition of immune complexes has been shown in vivo by the preventive effect of antihistaminic and antiserotonin drugs on the development of serum sickness to horse antidiphteric serum (Kniker et al. 1971). [Pg.94]

Being at the center of a complex network linking immune response and inflammatory reactions, it is not surprising that imbalances in KP metabolites lead to pathophysiological consequences. In Drosophila (Drosophila melanogaster), genetic deletions of individual KP enzymes resulted in neuronal abnormalities... [Pg.153]


See other pages where Immune complex reactions pathophysiology is mentioned: [Pg.1]    [Pg.820]    [Pg.593]    [Pg.1003]    [Pg.88]    [Pg.352]    [Pg.910]    [Pg.268]    [Pg.821]   
See also in sourсe #XX -- [ Pg.94 ]




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