Imines hydrogen compounds

Imines can be prepared in a similar manner by treatment of an active hydrogen compound with a nitroso compound ... 

N Alky] and N aryl imines have received the most attention in the literature, but significant research has also been performed in the area of "activated imines, that is, imines with electron withdrawing substituents at N. In addition to having different reactivity from N alkyl and N aryl imines, these compounds are intrinsically open to further functionalization after hydrogenation. The first of these compounds to be reduced enantioselectively were the N tosyl amines. In contrast to the related reaction with N alkyl and N aryl amines, the asymmetric hydrogenations of N tosyl amines are most often catalyzed by complexes of palladium. 

Fig. 3 Lewis add/base complexes of B(C6p5)3 (a) with active hydrogen compounds, (b) with hydrosilanes, and (c) with carbonyl groups and imines...

The EMA anhydride resins may be treated with iV,7V-dialkylaminoal-cohols to produce polyampholytes, ammonia, and primary or secondary amines to produce amides and a host of other mono and polyfunctional active hydrogen compounds to produce a wide variety of derivatives. The primary amine derivatives, i.e., amide-ammonium salts, may be transformed with heat to imide copolymers.Surface tension studies have been explored on EMA resins and octadecylamine derivatives of the copolymer.The effect of steric hindrance on accessibility, inhomogeneous consideration, electrostatic effects, etc., on the reaction of typical aliphatic amines and polymeric amines (polyethylene imine) with propylene-MA copolymer have been recently examined in great detail.The complexity of the reaction did not allow complete separation of the many variables. 

As a class of compounds, nitriles have broad commercial utility that includes their use as solvents, feedstocks, pharmaceuticals, catalysts, and pesticides. The versatile reactivity of organonitnles arises both from the reactivity of the C=N bond, and from the abiHty of the cyano substituent to activate adjacent bonds, especially C—H bonds. Nitriles can be used to prepare amines, amides, amidines, carboxyHc acids and esters, aldehydes, ketones, large-ring cycHc ketones, imines, heterocycles, orthoesters, and other compounds. Some of the more common transformations involve hydrolysis or alcoholysis to produce amides, acids and esters, and hydrogenation to produce amines, which are intermediates for the production of polyurethanes and polyamides. An extensive review on hydrogenation of nitriles has been recendy pubHshed (10). 

L = P(CH3)3 or CO, oxidatively add arene and alkane carbon—hydrogen bonds (181,182). Catalytic dehydrogenation of alkanes (183) and carbonylation of bensene (184) has also been observed. Iridium compounds have also been shown to catalyse hydrogenation (185) and isomerisation of unsaturated alkanes (186), hydrogen-transfer reactions, and enantioselective hydrogenation of ketones (187) and imines (188). 

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