Imaging of Lungs

The idea is based upon a relatively small device, being able to take up to 50 frames per second, connected with noninvasive sensors fixed to the skin and without being held by an operator but being able to monitor 24 h without intervention. 

The description is partly based on a booklet that appeared in 2011 Electrical impedance tomography The realization of regional ventilation monitoring (Teschner and Imhoff, 2011). The product is PulmoVista 500, fabricated and marketed by Drager, Germany. 

After 5 years of research, a small prototype series was built and spread out to selected 

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Coleman R. E., C. M. Laymon, and T. G. Turkington, FDG imaging of lung nodules A phantom study comparing SPECT, camera-based PET, and dedicated PET, Radiology, 1999 210 823-828. 

McAdams HP, Palmer SM, Donnelly LF, Charles HC, Tapson VF, MacFall JR. Hyperpolarized He-enhanced MR imaging of lung transplant recipients preliminary results. AJR Am J Roentgenol 1999 173 955-959. 

Hoffman EA, Reinhardt JM, Sonka M, Simon BA, Guo J, Saba O, Chon D, Samrah S, Shikata H, Tschirren J, Palagyi K, Beck KC, McLennan G. Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and function. Acad Radiol 2003 10(10) 1104-1118. 

Figure 8.7 (See color insert) Parametric images of lung [ F]-FHBG distribution in a rat administered adenovectors in a surfactant vehicle (A) or a saUne vehicle (B). The pixels within each ROI drawn on each slice were colored in pale blue. Pixels with radioactivity values greater than 0.3% of [ F]-FHBG ID/mL were colored in red. [ F]-FHBG = 9-(4-[ F]-fluoro-3-hydroxymethylbutyl)guanine. Note that higher levels of expression with the surfactant vehicle are apparent, without any specific spatial dependence. [Reproduced with permission from Richard et al. (41).]...

Figure 16.7 OCT images of lung after laser ablation (courtesy of Dr. S. Bopart).

Desbenoit, N., Saussereau, E., Bich, C., Bourderioux, M., Fritsch, J., Edehnan, A., BruneUe, A. and OUero, M. (2014) Localized hpidomics in cystic fibrosis TOF-SIMS imaging of lungs from Pseudomonas aeruginosa-infected mice. Int. J. Biochem. Cell. Biol. 52, 77-82. 

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