TOF-SIMS imaging

Fig. 3.16. High-resolution TOF SIMS images of silver bromide and silver chloride crystals.

Fig. 47. TOF-SIMS image highlighting cation-rich areas, indicating that local cathodic cells occur within the initiation zone. Image shows (A) total counts, (B) m/z = 40, (C) m/z = 52 and (D) m/z = 24. Reproduced by permission of John Wiley and Sons from Ref. [57. ...

Fig. 49. TOF-SIMS images showing that the cation-rich areas in the initiation zone do not corre.spond to polymer-rich areas (A) mjz. = 88 on 24 (B) tnjz = 77 + 91 on 24. Reproduced by permission of John Wiley and Sons from Ref. [571.

Valuable results with Tof-SIMS imaging have been obtained e.g., with paper samples. The distribution of papermaking chemicals on the surface of coated and uncoated papers is very important for its further treatment, such as printing. Figure 16 [70] is an example of use of the technique for chemical microscopy analysis of paper surfaces. 

Figure 16 ToF-SIMS images of total ion current, AKD (alkyl ketene dimer) size, optical brightener and hexosan distribution on multipurpose paper surface after coating with Au-Pd. Reproduced from Fardim and Holmbom [70], with permission from Elsevier. 2005.

Figure 15.3 Example of the use of a region of interest (ROI) on ToF SIMS images to obtain a more specific spectrum. On account of the selected area on the image, signals from fatty acids are emphasized on the selected spectrum (see colour Plate 3)...

Figure 15.14 Study of the sample from the Dogon statuette 71.1935.105.169. (a) Optical microphotograph (b) SEM micrograph showing the layer structure ToF SIMS images of (c) proteins, (d) polysaccharides and (e) stearic acid (f) superposition of the distribution of poly saccharides and stearic acid (see colour Plate 9)...

Figure 13.2. TOF-SIMS images of blue (m = 413 u) and green (m = 641 u) pigments of color filter array. Above each image the primary ion gun and the measurement time is displayed. Corresponding signal intensity of emitted secondary ions from an analyzed surface is given under suitable image. (Reprinted from Kollmer, F. 2004. Appl. Surf. Sci., 231-232 153-158. With permission from Elsevier.) (See color insert.)...

TOF-SIMS images (Figs. 13.5 and 13.6) illustrate the ability to detect changes in the dispersion (uniform or presence of metal clusters) of the active phase in supported-oxide catalysts. Figure 13.5 shows nearly uniform distribution of molybdenum. The surface contamination with NH4+ ions coming from a precursor, which were not removed during the catalyst preparation process, is also observed. Cobalt clusters in the range of several micrometers are clearly visible in Fig. 13.6. 

Figure 13.9. TOF-SIMS images of a silicon wafer taken from the fields 277 x 277 pm2 155 x 155 pm2, 39 x 39 pm2, and 7.8 x 7.8 pm2. On the highest magnification image the existence and distribution of trace impurities of ions such as Na, Ca, B02, and CxHy are observed. (See color insert.)...

Figure 9.46 ToF-SIMS images of Na, and of an poisoned single liver tumor cell - HepG2 cell. In the upper row are images of the HepG2 cell immersed in 2 4 solution in the lower ones the cells are in CuS04 solution - both solutions having a concentration of 15 p,M. (F. D. Mai, B. /. Chen, L C. Wu, F. Y. Li and W. K. Chen, Appl. Surf. Sci., 252, 6809 (2006). Reproduced by permission of...

B. Tyler, Interpretation of TOF-SIMS images multivariate and univariate approaches to image de-noising, image segmentation and compound identification, Appl. Surf. Sci., 203-204, 2003, 825-831. 

Gazi E, Dwyer J, Lockyer N, Gardner P, Vickerman JC, Miyan J, Hart CA, Brown M, Shanks JH, Clarke N (2004) The combined application of FTIR microspectroscopy and ToF-SIMS imaging in the study of prostate cancer. Faraday Discuss 126 41-59... 

Fig.10. TOF SIMS image of a lesion showing the variations in (a) calcium and (b) phosphorus across a lesion. The insets are TOF SIMS images of sound enamel. Note that the prismatic structure of enamel b is visible in the sound enamel.

The TOF SIMS images (fig. 10), like the EMPA data, show a small variation in the chemistry at the surface, with a subsurface layer that is generally... 

Which type of primary ion source can provide better static SIMS analysis Why do we not recommend using the smallest diameter of a primary beam for ToF SIMS imaging ... 

Figure 7.4. Time-of-flight secondary-ion mass spectroscopy (ToF-SIMS) image of the distribution of Fe on a cross section of a trembling aspen (Populus tremuloi desMmchx ) root embedded in clayey soil material. The Fe values are normalized to the total ion yield of the surface. The bar is 100 (im. (From Martin et al., 2004.)...

Yunus, S., Delcorte, A., Poleunis, C., Bertrand, P., Bolognesi, A., Botta, C. A route to self-organized honeycomb microstructured polystyrene films and their chemical characterization by ToF-SIMS imaging. Adv. Funct. Mater. 17(7), 1079-1084 (2007)... 

S. Perry and N. Winogard, High-iesolution TOF-SIMS imaging of eukaryotic cells preserved in a trehalose matrix. Anal Chem. 77, 7950-7957 (2005). 

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