Image processing, drug delivery

Figure 3. Microfluidic Device. (A) Time lapse illustrating repulsion the ejection of 1.9 pm fluorescent polystyrene microsphere particles from an electroactive microwell. After dissolution of the membrane, the fluorescent particles can be seen in the well. White hnes outline the gold electrodes features. Images are taken every 2 s (total of 10 s). (B) Schematic of the electroactive microwell drug delivery system developed here. Scale bar represents 2 mm. (C) Micro fluidic device with electrical leads connected to thin copper wires. Inset Magnified view of microchip from above looking at the region near the membrane. (D) To illustrate the electrokinetic transport processes involved in the ejection stage, a finite element analysis of time-dependent species transport of the system is shown. Images show cut view of species concentration every 60 s up to 300 s after the ejection process.

The magnetic latex can be utilized in therapeutic processes, for example magnetic resonance imaging (MRI) [18], targeted drug delivery [19, 20] and hyperthermia [21]. 

In the past, QDs have been used extensively for intracellular applications such as, cell imaging and the labeling of subcellular compartments, and these topics have been recently reviewed [201, 202]. The use of cell-incorporated QDs to probe drug delivery or to follow intracellular processes is, however, scarce, and the subject holds great promise for future developments. One major challenge would involve the use of... 

In drug discovery and development, it is a crucial process to determine how a candidate compound is distributed and metabolized within the body. The use of IMS to monitor drug delivery and their metabolism has also been attractive application area. IMS offers detailed drug distribution images, which are comparable to traditional whole body autoradiography (WBA) technique using radiolabeled compounds (Figure 3.24). Stoeckli... 

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