I-Antigenic determinant

Hoffman, S. and Edelman, G.M. (1987) A proteoglycan with HNK-I antigenic determinants is a neuron-associated ligand for cytotactin. Proc. Natl. Acad. Sci. USA 84 2523-2521. 

Feizi, T., E.F. Hounsell, J. Alais, A. Veyrieres, and S. David. 1992. Further definition of the size of the blood group-I antigenic determinant using a chemically synthesised octasaccharide of poly-N-acetyllactosamine type. Carbohyd. Res. 10 289-297. 

Moudgil, K. D., Sercarz, E. E. and Grewal, I. S. (1998), Modulation of the immunogenicity of antigenic determinants by their flanking residues , Immunol. Today, 19, 217-220. 

Dolovich J, Evans SL, Nieboer E. 1984. Occupational asthma from nickel sensitivity I. Human serum albumin in the antigenic determinant. Br J Ind Med 41 51-55. 

Does not identify those patients who react to a minor antigenic determinant (i.e., anaphylaxis) does not reliably predict the occurrence of late reactions patients with a negative skin test may still have allergic reactions to therapeutic penicillin... 

Dideoxyhexoses. Several bacterial antigenic determinants with the general structure of 3,6-dideoxyhexoses occur in the cell wall of Pasteurella and Salmonella strains. Most of the transformations reported so far occur as cytidine nucleotides (see Table I, References 15, 16, 17, 18, 19). Here, again the first step is the transformation of the cytidine diphospho-linked glucose into its corresponding 4-keto derivative. By at least two distinct steps, requiring NADPH, reduction to several different 3,6-dideoxyhexoses have been reported. One 3,6-dideoxyhexose CDP-tyvelose (3,6-dideoxy-D-arabino hexose) is formed by a specific 2-epimer-ase from CDP-paratose (24). 

The Chemical Synthesis of 2-D-(a-i.-fucopyranosyl)-3-(3-(a-D-galactopyranosyl)-D-galactose. The Terminal Structure of the Blood-Group B Antigenic Determinant. R. U. Lemieux and... 

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