I amines

CbH)I [AMINES - CYCLOALIPHATIC AMINES] (Vol2) trans-1,4-Cyclohexane diisocyanate [7517-76-2]... 

Thermoplastic urethane adhesives may be processed into an adhesive film. I,amination of two substrates can, in theory, be done immediately, but the film is often extruded onto one substrate, covered by a release liner, and allowed to cool. Crystallization follows to create a non-tacky film that may be cut into specific shapes. The release liner is then removed, and the shaped adhesive can be heat-activated on one substrate, using infrared lamps. The second substrate is then nipped under pressure, followed by a cooling press to speed crystallization. Once the backbone has crystallized, the bond should be strong. 

Chloro-4-pentanone N-Ethyl-N-2-hydroxyethy I amine 4,7-Dichloroquinoline Sulfuric acid... 

To a 0.02-0.05 M soln of (1 / , l R)-(2-hydroxy-l-phenelhyl)( I-arylalky I (amine 5 in CH2C12/CH,0H (2 1) at 0 C is added, in one portion, 1 equiv of Pb(OAc)4. The mixture is stirred for 2-20 min, then 5 ntL of a 15% aq solution of NaOlI is added. The aqueous layer is separated, extracted with CH,C1, and the combined organic extracts are evaporated in vacuo. Then the residue is dissolved in Ei,0 and stirred for 4-16 h wilh an equal volume of 3 N aq HC1. Subsequently, the aqueous phase is basified by the addition of Na2C02 and extracted with Et,C>. After drying over MgS04 and removal of the solvent the crude amine 6 is purified by Kugclrohr distillation or Hash column chromatography yield 46 - 65% 92- >99% ee. 

Adamek and Hajek [83] reported that the addition of CC14 and CCl3C02Et to styrene in the presence of a homogeneous Cu(I)-amine catalyst in acetonitrile (Scheme 4.33) occurred more rapidly under MW heating than conventional heating. 

Few studies have systematically examined how chemical characteristics of organic reductants influence rates of reductive dissolution. Oxidation of aliphatic alcohols and amines by iron, cobalt, and nickel oxide-coated electrodes was examined by Fleischman et al. (38). Experiments revealed that reductant molecules adsorb to the oxide surface, and that electron transfer within the surface complex is the rate-limiting step. It was also found that (i) amines are oxidized more quickly than corresponding alcohols, (ii) primary alcohols and amines are oxidized more quickly than secondary and tertiary analogs, and (iii) increased chain length and branching inhibit the reaction (38). The three different transition metal oxide surfaces exhibited different behavior as well. Rates of amine oxidation by the oxides considered decreased in the order Ni > Co >... 

V-Methyl-/V-(2-perlhioroalkyl)ethy I amines 17 (R = C4F9, QT n or C-xI i 7) were prepared from the azides 16 by sequential reaction with triphenylphosphine, methyl iodide and aqueous potassium hydroxide45. 

The fact that complex 38 does not react further - that is, it does not oxidatively add the N—H bond - is due to the comparatively low electron density present on the Ir center. However, in the presence of more electron-rich phosphines an adduct similar to 38 may be observed in situ by NMR (see Section 6.5.3 see also below), but then readily activates N—H or C—H bonds. Amine coordination to an electron-rich Ir(I) center further augments its electron density and thus its propensity to oxidative addition reactions. Not only accessible N—H bonds are therefore readily activated but also C—H bonds [32] (cf. cyclo-metallations in Equation 6.14 and Scheme 6.10 below). This latter activation is a possible side reaction and mode of catalyst deactivation in OHA reactions that follow the CMM mechanism. Phosphine-free cationic Ir(I)-amine complexes were also shown to be quite reactive towards C—H bonds [30aj. The stable Ir-ammonia complex 39, which was isolated and structurally characterized by Hartwig and coworkers (Figure 6.7) [33], is accessible either by thermally induced reductive elimination of the corresponding Ir(III)-amido-hydrido precursor or by an acid-base reaction between the 14-electron Ir(I) intermediate 53 and ammonia (see Scheme 6.9). 

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