Hyphenated chromatographic techniques

It is generally difficult to identify developments with high potential where interferences do not preclude general application. To ensure the relevance of a method, its application to real sample analysis must be demonstrated. The accuracy of an analytical method should be confirmed by an independent method, or by the analysis of certified reference materials. Detailed comparative studies of the method developed with other well-established methods for polymer/additive analysis are not frequent in the analytical literature. Nevertheless, some examples may be found in Section 3.6. Improvements in analytical techniques are reasonably sought in sample preparation and in hyphenated chromatographic techniques. However, greatest efficiency is often gained from the use of databases rather than accelerated extraction or hyphenation. 

T Hyphenated Chromatographic Techniques in Nuclear Magnetic Resonance Spectroscopy... 

Examines hyphenated chromatographic techniques with nuclear magnetic resonance spectroscopy... 

Hyphenated chromatographic techniques of various types (e.g., HRGC/HRGC and HPLC/HRGC) are being used in conjunction with a variety of detectors to improve detectability, increase specificity, and reduce cleanup costs for routine analysis. Vuruls et al. (1992) reported ng/L quantitation for aqueous atrazine samples by LC/GC/MS. 

Both Soderstrom et al. (25) and Creasy et al. (26) have applied GC/FTIR together with several other hyphenated chromatographic techniques to analyze CWC-related chemicals in complex matrices. The results of the different technique have been combined to unequivocally identify the relevant chemicals in low concentrations. In both studies, IR and MS spectra have been used together in spectral interpretation. Weimaster et al. (70) studied samples collected in Iraq, using a very wide variety of instrumentation, but they could not find any scheduled chemicals. 

Exarchou V, Eiamegos YC, van Beek TA, Nanos C, Vervoort J (2006) Hyphenated chromatographic techniques for the rapid screening and identification of antioxidants in methanolic extracts of pharmaceutically used plants. J Chromatogr A 1112(l-2) 293-302. 

Many techniques can be employed in the analysis of compounds that can be used in the manufacture of explosives and explosive materials. Raman and infrared spectroscopy, nuclear magnetic resonance (NMR), mass spectrometry, and gas chromatography can all be used in the analysis of this type of material. Hyphenated chromatographic techniques, such as GC-MS and LC-MS, can also be used. 

This is undoubtedly the most important class of L-histidine derivatives only because of pilocarpine s (27) therapeutic uses [8, 23, 24]. Since Byasson s first report of jaborandi alkaloids isolation from the leaves of Pilocarpus spp. (Rutaceae) [8], in 1875, several other imidazole alkaloids have been reported in this genus. The identification of these was facilitated due to recent advances in hyphenated chromatographic techniques such as HPLC—ESI—MS/MS (high performance liquid chromatography with electrospray ionization tandem mass spectrometry). 

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