Hydroxyproline betaines

The stereochemistry of the hydroxyproline betaines, betonicine and turicine, had not been previously established this has now been done by the use of nonepimerizing methylating conditions on hydroxyprolines of known stereochemistry. 

By using a modification of a reaction discovered by Traube and Lehmann (61,62), Leuchs, Giua, and Brewster (63) synthesized 4-hydroxy-proline from a-carbethoxy-a, 5-dichloro-y-valerolactone from which Leuchs and Brewster (64) prepared Z-hydroxyproline by resolution with the aid of quinine. On methylation of a sample of Z-hydroxyproline thus prepared, Kiing (65) obtained a mixture of optically active betaines which he separated by fractional crystallization into a levorotatory betaine identical with betonicine and a dextrorotatory betaine identical with turicine. Betonicine is, therefore, the methyl betaine of 4-hydroxyhygrinic acid (XXIV). Betonicine and turicine possess different solubilities and can be separated... 

Dipalmitoyl hydroxyproline Disodium lauroamphodiacetate Disodium lauroamphodipropionate N,N-Distearyl-N-methyl-N-(3-sulfopropyl)-ammonium betaine ... 

Bisisostearamidopropyl ethoxyethyl dimonium chloride Capryloyl hydrolyzed collagen Dipalmitoyl hydroxyproline Disodium lauroamphodiacetate Olivamidopropyl betaine... 

Behenamidopropyl PG-dimonium chloride Dipalmitoyl hydroxyproline Disodium oleth-3 sulfosuccinate Palmitoyl collagen amino acids Undecylenoyl collagen amino acids surfactant, bath oils Isostearoyl hydrolyzed collagen surfactant, bath oils blooming Myreth-3 myristate surfactant, beverages Licorice (Glycyrrhiza glabra) root extract surfactant, biocides Cocamidopropyl hydroxysultaine N,N-Dimethyl-N-lauric acid-amidopropyl-N-(3-sulfopropyl)-ammonium betaine N,N-Dimethyl-N-myristyl-N-(3-sulfopropyl)-ammonium betaine N,N-Dimethyl-N-palmityl-N-(3-sulfopropyl)-ammonium betaine N,N-Dimethyl-N-stearyl-N-(3-sulfopropyl)-ammonium betaine... 

Dimethicone copolyol behenate Dimethicone propyl PG-betaine Dioctyidodecyl stearoyl glutamate Dipalmitoylethyl hydroxyethylmonium methosulfate Dipalmitoyl hydroxyproline Disodium iauroamphodiacetate Hydrolyzed collagen Palmitoyl collagen amino acids Paimitoyi keratin amino acids Potassium cetyi phosphate... 

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