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Hydroxyl group drug-receptor interactions

The formation of an ionic bond results from the electrostatic attraction that occurs between oppositely charged ions. The strength of this bond is considerably less (5 kcal/mole) than that of the covalent bond and diminishes in proportion to the square of the distance between the ionic species. Most macromolecular receptors have a number of ionizable groups at physiological pH (e.g., carboxyl, hydroxyl, phosphoryl, amino) that are available for interaction with an ionizable drug. [Pg.12]

See other pages where Hydroxyl group drug-receptor interactions is mentioned: [Pg.386]    [Pg.248]    [Pg.34]    [Pg.29]    [Pg.19]    [Pg.476]    [Pg.331]    [Pg.476]    [Pg.883]    [Pg.9]    [Pg.45]    [Pg.184]    [Pg.884]    [Pg.99]    [Pg.595]    [Pg.67]    [Pg.203]    [Pg.528]    [Pg.530]    [Pg.56]    [Pg.249]    [Pg.1133]    [Pg.68]    [Pg.227]    [Pg.601]    [Pg.823]    [Pg.257]    [Pg.435]    [Pg.75]    [Pg.202]    [Pg.162]    [Pg.105]    [Pg.404]    [Pg.283]    [Pg.673]    [Pg.1667]    [Pg.4]    [Pg.283]    [Pg.284]   
See also in sourсe #XX -- [ Pg.476 , Pg.476 ]

See also in sourсe #XX -- [ Pg.476 , Pg.476 ]



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Drug receptor interaction

Drug-receptor

Hydroxyl interaction

Interaction group

Receptor interaction

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