3-Hydroxybutyrate-3-hydroxyvalerate

Poly(3-hydroxybutyrate—3-hydroxyvalerate) [80181 -31 -3] resin, produced from a bacterium during a sugar fermentation process, has been reported to be biodegradable, and its target markets include "flushables" such as feminine hygiene products and disposable diapers (99). 

During aging of PHVB in sterile water at pH 7 and 60 °C, 2-butenoic acid (crotonic acid), 2-pentenoic acid, 3-hydroxybutyric acid, 3-hydroxyvaleric acid, 3-hydroxybutyrate dimer, 3-hydroxybutyrate-3-hydroxyvalerate dimer and 3-hydroxyvalerate dimer were formed [99]. The weight loss was, however, only 2% after 200 days at 60 °C. Monomers, oligomers and derivatives, produced by dehydration at the OH-terminus were identified after alkaline hydrolysis of PHB [110]. In accordance CZE showed that the accelerated hydrolysis of PHB leads to the formation of hydroxyacid oligomers and a series of peaks formed by a side reaction leading to a C=C bond at the noncarboxylic acid end [111]. Kinetics of the abiotic hydrolysis of PHB in acid and alkaline media were monitored by following the forma-... 

S. Yoshioka, A. Kishida, S. Izumikawa, Y. Aso, and Y. Takeda, Base-induced polymer hydrolysis in poly( 3-hydroxybutyrate/ 3-hydroxyvalerate) matrices, J. Contrail. Release 16,341-348 (1991). 

Myshkina, V. L. et al. Biosynthesis of poly-3-hydroxybutyrate-3-hydroxyvalerate copolymer by Azotobacter chroococcum strain 7B. Appl. Biochem. Microbiol. 2010, 46(3), 289-296. 

Doi, Y., Tamaki, A., Kunioka, M., and Spga, K., 1987, Biosynthesis of topolyestas of 3-hydroxybutyrate, 3-hydroxyvalerate, and 5-hydroxyvalerate in Alcaligenes eutrophus from 5-chloropentanoic and pentanoic acids. Makromol. Chem., Rapid Commun. 8 631... 

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