Hydroxy formation

The epoxides may be converted into 1 2-glycols by hydrolysis. In some cases the 1 2-glycol may be produced directly by carrying out the epoxidation in the presence of water. If the 1 2-glycol is desired, it is usually better to employ performic acid or peracetic acid, the latter best in the presence of a trace of sulphuric acid. An epoxide is first formed, followed by the hydroxy-formate or hydroxy-acetate, and ultimately the 1 2-glycol ... 

E rido[2,3-b]pyrazine, 2,3-dihydroxy-chlorination, 3, 251 Pyrido[2,3-b]pyrazine, 6-hydroxy-formation, 3, 251... 

These results also raise a number of interesting general questions related to the stability of surface species when more than one kind of species is present. For example, OH groups on copper are unstable above 200 K, whereas CuOH-COOH is stable above room temperature hydroxylation of lead by H20(g) is not feasible, whereas PbOH COOH is stable at the same temperature in vacuo. The analogy between the surface hydroxy formate (Fig. 16) and ethylene interaction with CuO is striking. 

Pyrido[2,3-b]pyrazine, 2,3-dihydroxy-chlorination, 3, 251 Pyrido[2,3-b]pyrazine, 6-hydroxy-formation, 3, 251 Pyrido[2,3-b]pyrazine, 8-hydroxy-tautomerism, 3, 250 Pyrido[2,3-b]pyrazine, methyl-acylation, 3, 253 Pyrido[2,3-b]pyrazine, 2-oxo-oxidation, 3, 250-251... 

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