1- Hydroxy, 2,3-epoxy chlordene

The primary metabolism of heptachlor is in the liver where microsomal enzymes convert the parent compound to the more toxic heptachlor epoxide as well as to the less toxic metabolites l-chloro-3-hydroxychlor-dene, 1-hydroxychlordene, and 1-hydroxy-2,3-epoxy-chlordene. These latter metabolites are also more easily excreted. Both heptachlor and heptachlor epoxide are stored in adipose tissue and in the liver, kidney, and muscle tissues. The epoxide is the primary storage form. Heptachlor is able to cross the placenta and has been found in human milk. Metabolites of heptachlor are excreted in urine and feces. 

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