Hydrophobicity scanning electrochemical microscopy

Recently new methods, based on petturbations on the linear sweep voltammetry response of the mediator in the presence of the protein," a mediated thin-layer voltammetry technique, cyclic voltammetric simulation apphed to an electrochemically mediated enzyme reaction" have been setded to gain information on the protein-mediator interactions. More recendy the Scanning Electrochemical Microscopy (SECM) was used to probe the red-ox activity of individual cells of purple bacteria, by using two groups of mediators (hydrophilic and hydrophobic species) in order to gain information on the dependence of measured rate constant on the formal potential of the mediator in solution. By this technique an evaluation of the intracellular potential was also performed. ... 

Shul, G., Nogala, W., Zakorchemna, L, Niedziolka, J., Opallo, M. Scanning electrochemical microscopy study of ion transfer process across water/2-nitophenyloctylether interface supported by hydrophobic carbon ceramic electrode. J. Solid State Electrochem. 2008, 12, 1285-1291. 

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