Hydrophobic interaction chromatography surface chemistry

Capture array involves the immobilization of non-protein molecules onto the surface which can interact with proteins in the solute phase. Generally, capture molecules may be broad capture agents based on chromatography type surface chemistries such as ion exchange, hydrophobic and metal affinity functionality, or they may be highly specific such as molecular imprinted polymers or oligonucleotide aptamers. 

POROS media, made by copolymerization of styrene and divinylben-zene, have high mechanical strength and are resistant to many solvents and chemicals. The functional surface chemistry of the particles can be modified to provide supports for many types of chromatography, including ion exchange, hydrophobic interaction, immobilized metal affinity, reversed... 

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