Hydrophobic cluster analysis

CBH I 497 core-BA aa sequence in part from protein and in full from gene (cbhl), number and location of SS bridges, region of O-glycosylation, types of carbohydrate, papain cleavage site, hydrophobic cluster analysis, computer model of active site, 2D-NMR on a synthetic tail fragment, SAXS on whole CBH I, head domain and xylan/CBH I complex... 

EG I 437 core-BA aa sequence in part from protein and in full from gene (egll), hydrophobic cluster analysis, SAXS not successful... 

Henrissat, B., Claeyssens, M., Tomme, P., Lemesle, L., and Mornon, J.-P. 1989. Cellulase families revealed by hydrophobic cluster analysis. Gene, 81,83-95. 

Hydrophobic cluster analysis is a sequence comparison and aligmnent method introduced by Gaboriaud and others in 1987 [12]. The method relies upon two-dimensional representation of protein sequences to determine regions of probable structural similarity. The method has been successfully applied [5,17,21] to detect regions of structural similarity even in proteins with little sequence identity and when little or no three-dimensional information is available. 

Hydrophobic cluster analysis (HCA) is a very efficient method to analyse and... 

Gaboriaud, C., Bissery, V., Benchetrit, T. Momon, J.P. ( 9%1) FEBS Lett., 224, 149-155. Hydrophobic Cluster Analysis an efficient new way to compare and analyse amino acid sequences. 

Hydrophobic cluster analysis revealed that truncation of the large subunit increases the solvent accessibility for some residues such as and L 2A spatial proximity of these residues and their... 

Hydrophobic cluster analysis (HCA) is a very efficient method to analyse and compare protein sequences. Schematically, HCA uses a highly degenerated code for the sequences, where only two main states are initially considered hydrophobic andhdrophilic. 

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