Hydrophilic polymers tissue engineering

The ability of hydrophilic polymers, specifically PEG, to provide a substrate material that is essentially a blank slate is extremely valuable in both investigations of the nature of cell-substrate interactions as well as in the creation of well-defined biomaterials and tissue engineering scaflblds. In this marmer, PEG serves as an ideal material which can be modified to contain numerous biological signals. 

Hydrophobicity of biomedical polymers influences the biocompatibility depending on the particular application such as tissue engineering, blood contacting devices, and dental implants [35]. Polymers are dynamic structures and can switch their surface functional groups depending on the environment. For example, polymeric biomaterials need to have a hydrophilic smface for most of the applications, so that the cell-adhesive proteins present in the serum will be adsorb and promote cell adhesion and proliferation. This is achieved by snrface treatment procedures such as... 

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