75-13-8 hydrogen cyanate

Formula CHNO MW 43.03 CAS [420-05-3] Structure N C—OH Synonym cyanic acid 

Hydrogen cyanate is a severe irritant to the eyes, skin, and mucous membranes. Exposure to this compound can cause severe lacrimation. Inhalation can produce irritation and injnry to the respiratory tract. LD50 valnes are not reported. 

Flammable the liquid can explode when heated rapidly. 

Hydrogen cyanate can be disposed of in the drain in small amounts. It decomposes in water forming CO2 and NH3. 

Hydrogen cyanate can be analyzed by measuring its decomposition products CO2 by GC/TCD or NH3 by colorimetry. 

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Formula HCNO MW 43.03 Structure N=C-0-H Synonym hydrogen cyanate... 

Cyanates and Thiocyanates.—Three reasonable structures can be written for hydrogen cyanate ... 

HFA forms an adduct 102 with hydrogen cyanate that decomposes above 0°C. Storage over a long period produces oxadiazinedione 103 and loss of one molecule of HFA (143). 

When primary amines (43 R = H) are used as the amine component, hydantoinimides (42e) and thiohy-dantoinimides (42f) result from hydrogen cyanate and thiocyanate as the acid component The... 

When primary amines (43 R6 = H) are used as the amine component, hydantoinimides (42e) and thiohy-dantoinimides (42f) result from hydrogen cyanate and thiocyanate as the acid component HX.53,54 The most important acid components are the carboxylic acids. With primary amines (43 R6 = H) they yield a-acylaminocarboxamides (42g),39,55-57 whereas with secondary amines (42 R1, R2 = organyl), the di-acylimines (42h) are the products, provided that acylatable nucleophiles are absent.55,58,59 The diacyl-imides (42h) are acylating reagents that transfer an R CO group, and so are their precursors, the a-adducts (41 X = R CCh).55... 

Two acids can be derived from 13.34 HOCN (cyanic acid or hydrogen cyanate) and HNCO (isocyanic acid, 13.35). It has been established that HOCN and HNCO are not in equilibrium with each other. Isocyanic acid (pA), = 3.66) is obtained by heating urea (equation 13.81) but rapidly trimerizes, although heating the trimer regenerates the... 

Ethyl carbamate in wine is formed (mostly at the end of fermentation) from urea. The intermediates of its degradation are probably cyanates and cyanic acid (HO-C=N), also known as hydrogen cyanate, which may isomerise to isocyanic acid (H-N=C=0). Iso-cyanic acid can also arise by protonation of the cyanate anion and nucleophilic addition of ethanol to isocyanic acid yields ethyl carbamate. Isocyanic acid also reacts with other nucleophilic reagents, such as water (with formation of ammonia and carbon dioxide), thiols and amino groups of proteins. By catalysis with ornithinecar-bamoyl transferase, citrulline is transformed into ornithine and carbamoyl phosphate, the ethanolysis of which yields ethyl carbamate (Figure 12.39). 

Hydrogen cyanide can also be converted to cyanoacetylene and hydrogen cyanate, both precursors of pyrimidines. These reactions were reproduced in the laboratory. In fact, in 1828, F. Wohler made urea from hydrogen cyanate and ammonia, the first synthesis of an animal substance from inorganic materials. Very likely, all these processes occurred primarily in an aqueous environment where and OH" ions acted as specific-acid or specific-base catalysts. It is particularly impressive that the three major classes of nitrogen containing biomolecules, purines, pyrimidines, and amino acids are formed by the hydrolysis of the oligomers formed directly from... 

Hexachloropentadiene dimer 7878 Hydrogen cyanate 2502 secostrycbnidine-10,16-dione 10839... 

Add hydrogen cyanate to acetylene under the existence of copper chloride (I) catalyst. 

Low-temperature photolysis of solids containing HNCO has been shown to make H-0-C=N, known as cyanic acid or hydrogen cyanate it is a tautomer of isocyanic acid. 

Cyanic Acid hydrogen cyanate 2 Not recommended severe effect Polyacetal BITS... 

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