Hydrochloric acid, removal

The washing with concentrated hydrochloric acid removes unchanged alcohol, if present. 

The fraction of oil of cade boiling at 260° to 280° is converted into cadinene dihydrochloride by saturating its solution in dry ether with dry hydrochloric acid gas. The hydrochloride is separated, dried, and leorystallised, and the hydrochloric acid removed by heating it with aniline or with sodium acetate in glacial acetic acid. The liberated cadinene is rectified in a current of steam. Cadinene from oil of cade is highly laevo-rotatory, the dextro-rotatory variety being obtained from Atlas cedar oil and West Indian sandalwood oil. 

The synthesis of various allyl derivatives of di-i-butyl iminodicarboxylate 21 from its lithium salt and allyl acetates under Pd(0) catalysis has been described. Rearrangements have been observed in some reactions, e.g. equation 19. The products are cleaved to t-butoxycarbonylamines by trifluoroacetic acid at room temperature dilute hydrochloric acid removes the second protecting group54. 

Zinc and hydrochloric acid remove the ring sulfur from 5-amino-1,2,4-thiadiazoles as hydrogen sulfide.6,85 5-Anilino-3-phenyl-l,2,4-thiadiazole (189) is slowly degraded, by the same reagent, to N-benzyl-N -phenylthiourea (191),129 probably by the usual ringopening at the N—S bond, followed by the further reductive hydrolysis of the intermediate (190) the latter can indeed be similarly reduced.129... 

Final treatment of the host material with hydrochloric acid removes some of the extra-framework aluminium in order to make room for guest molecules. The overall procedure is described elsewhere in detail11.15. 

Nickel Triphosphide, NiPs, results 3 on heating an alloy of nickel and tin, containing 5 per cent, of nickel, with more than 20 per cent, of its weight of phosphorus in a sealed tube to 700° C. Tin triphosphide, SnP3, is simultaneously produced, but may be decomposed by heating the mixture under reduced pressure at 360° C. Treatment with hydrochloric acid removes the products, leaving the triphosphide as a crystalline residue, of density 4-19 at 18° C. 

Cleaning Up Neutralize the aqueous layer with 10% hydrochloric acid, remove the tin hydroxide by filtration, and discard it in the nonhazardous solid waste container. The filtrate should be diluted with water and flushed down the drain. Sodium sulfate, after the ether evaporates from it, can be placed in the nonhazardous waste container. 

Diacetoxymercuri - 4 ethoxy - 1 - diacetoxymercuri-phenyl-2 3-dimethyl-5-pyrazolone is prepared in a similar manner to the 4-methoxy compound, but the methyl alcohol in the latter preparation is now replaced by ethyl alcohol. Yield 96-6 per cent. It forms small, colourless needles vhich crystallise with 1 mol. of water, which may be removed by heating in vamo over phosphorus pentoxide at 110° C. It has similar solubilities to the methoxy compound, and hydrochloric acid removes the mercury in the 4-position. 

A variety of diverse synthetic methods have been empioyed for the preparation of cyclopropane (1 j. Schlatter and Demjanov and Dojarenko pyrolyzed cyclopropyltrimethylammonium hydroxide at 320°C using platinized asbestos as the catalyst. About equal amounts of cyclopropene (1) and cyclopropyidimethylamine are formed, contaminated with some dimethyl ether and ethylene. Treatment with dilute hydrochloric acid removed the amine from the gas stream and 1 was separated from the other products by gas chromatography. Alder-Rickert cleavage of the Diels-Alder adduct formed from cycloheptatriene and dimethyl acetylenedicarboxylate resulted only in the formation of a polymer and trace amounts of 1. A simple approach by Closs and Krantz based on the synthesis of 1-methylcyclopropene involved the addition of allyl chioride to a suspension of sodium amide in mineral oil at 80°C. Under the conditions employed, 1 could readily escape from the reaction mixture. Though a number of variations were tried, the yield of 1 never exceeded 10%. 

With modification, the aforesaid method can sometimes be applied to the resolution of a neutral compound. Such a resolution is accomplished by first converting the neutral compound into a derivative which can form a salt. Resolution of dl-octanol-2 is an example of the application of this modification. The racemic mixture of the alcohol is converted by treatment with phthalic anhydride into the acid phthalate. In the next step the acid phthalate is reacted with the naturally occurring laevorotatory base, brucine. Fractional crystallisation of the resulting mixture of the brucine salts yields the separated salts. Decomposition of the separated salts with hydrochloric acid removes brucine, and the two resulting acid phthalates are then hydrolysed with alkali to get the d- and 1-forms of octanol-2. 

Tsutsui and Zeiss (90) showed that when diphenylacetylene was added to a solution of an unstable nickel(II) compound, dimesitylnickel, at low temperatures, an orange material with a composition close to that required for (diphenylacetylene)4Ni and hexaphenylbenzene were obtained. The orange material was quite intractable hydrochloric acid removed the nickel to give an organic material which was also insoluble and intractable. The authors suggested that this might be a bis(tetraphenylcyclobutadiene)nickeI, but insufficient evidence is available. 

A number of other lead separations have been described In the recent review by Schlndewolf (S12). These Include separations from Indium and antimony on Dowbx-5P by loading In 0.1 M hydrochloric acid, removal of antimony with 0.2 M,... 

Despite many attempts 12 failed to undergo the Wittig reaction necessary for the introduction of the double bond between C10 and Cl 1. As this may have been due to the acidic hydrogen at C2, reduction of the ester functionality to an alcohol was carried out, as shown in Scheme 3. The methyl ketone 13 was treated with ethylene glycol and then reduced with lithium aluminum hydride, at -15 0 to give the alcohol 14. Hydrochloric acid removed the ketal and protection under the usual conditions with t-butyidimethylsilylchloride gave 15 in an... 

A wash with concentrated hydrochloric acid removes the dangerously explosive nitrogen trichloride [209]. Scrubbing with liquid chlorine (see Fig. 80) mainly reduces the content of organic impurities and carbon dioxide, but it can also lower the bromine content. When the chlorine is cooled down to near its dew point, liquid chlorine scrubbing is often combined with compression by turbo or reciprocating compressors. 

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