Hyaluronic Acid Coating on Three-dimensional Porous Scaffolds

1 Hyaluronic Acid Coating on Three-dimensional Porous Scaffolds 

Without growth factors, a mixture of HA, methylated collagen, and terpolymer was used to coat porous PCL meshes by polyelectrolyte complex coacervation [111]. The coated scaffolds supported better cell seeding efficiency and distribution as well as led to an upregulation of osteogenic gene expression (alkaline phosphatase, osteocalcin, and bone sialoprotein I and II) by MSC in vitro [111]. 

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