Human viscera sample

Human viscera (endrin) Extraction of homogenized sample with diethyl ether, volume reduction and clean-up using column chromatography on charcoal, alumina, and sodium sulphate elution using ethyl ether solvent removal and redissolution in acetone TLC No data No data Ganguly and Bhattacharyya 1973... 

In addition to the silica-based materials mentioned above, modem polymers are widely used for TTA and QTA sample preparation allowing SPE not impaired by undesirable silanol activities. HLB Oasis (Waters) is the tradename for a hydrophilic-lipophilic balance reversed-phase sorbent enabling lipophilic interaction to benzene moieties and hydrophilic interactions to pyrrolidone groups as present in the macroporous copolymer of poly(divinylbenzene-co-iV-vinylpyrrolidone). Elution of analytes is often performed with solvents containing MeOH or ACN. Applying this adsorbent TA such as atropine and scopolamine were extracted from human viscera [15], human serum [97-99], human urine [12] as well as from rat plasma and brain microdialysate [77], Furthermore, this hydrophilic-lipophilic balance phase was also suitable for extraction of the QTA trospium from human and rat plasma [77, 84] and methyl scopolamie from rat plasma [77] (Table 4). 

Samples were also taken from the geoduck beds for PSP analysis ( 3). Spot check samples were taken, with results indicating that high levels existed only in the viscera of the clam. Of all samples taken, only one sample of body meat taken near Gravina Island (Ketchikan, 1980) revealed PSP levels above the quarantine limit of 80 mg/100 g for human consumption. 

The human biological materials may be solid (bone, teeth, hair, nails, tissue), semisolid (blood, faeces, viscera) or liquids (body fluids). Treatment of the solid samples usually demands some extra steps during sample manipulation, e.g. particle size reduction, homogenisation, sub-sampling etc. Heterogeneous liquid phases, e.g. blood and certain body fluids, additionally need stabilisation and homogenisation so as to avoid occurrence of any changes in their composition, prior to actual analysis (Anand et al., 1975). It is also advisable to keep the total number of transfers to a minimum, and use accessories made of non-wettable and inert materials in case of the liquids. 

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