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Human vascular endothelial growth factor

The antibody brings about its effect by inhibiting angiogenesis (the formation of new blood vessels), a process required to support tumour growth. Specifically, the antibody binds human vascular endothelial growth factor. This prevents the latter from binding to its cell surface receptor, a process central to triggering new blood vessel formation in both normal and diseased tissue. [Pg.394]

Shibata, T., Akiyama, N., Noda, M., Sasai, K. and Hiraoka, M. (1998) Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes. Int.J. Radiat. Oncol. Biol. Rhys., 42, 913-916. [Pg.28]

E. R. McCluskey, andT.F. Zioncheck. 2002. A target-mediated model to describe the pharmacokinetics and hemodynamic effects of recombinant human vascular endothelial growth factor... [Pg.41]

Hendel RC, Henry TD, Rocha-Singh K, et al. Effect of intracoronary recombinant human vascular endothelial growth factor on myocardial perfusion evidence for a dose-dependent effect, Circulation 2000 101 1 18-121,... [Pg.403]

S. M. Eppler, D. L. Combs, T. D. Henry, J. J. Lopez, S. G. EUis, J.-H. Yi, B. H. Annex, E. R. McCluskey, and T. F. Zioncheck, A target mediated model to describe the pharmacokinetics and hemodynamic effects of recombinant human vascular endothelial growth factor in humans. Clin Pharmacol Ther 72 20-32 (2002). [Pg.870]

Human vascular endothelial growth factor 30 mgr cell culture (moss Ph. patens) 82... [Pg.895]

The productivity of moss bioreactor for human vascular endothelial growth factor (hVEGF) reached 30 mg per day [82]. The company claims that further increases in yield can be achieved by optimization of production strains for specific proteins. [Pg.905]

Duenas ET, Park A, Daugherty A, Kahn J, Kowalski J, Cuthbertson A, Cleland JL Development of poly-(D,L-lactide-co-glycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis, J Control Release 2001, 69, 13-24. [Pg.1387]

Recombinant hormone 14 Recombinant human vascular endothelial growth factor, see rhVEGF Recombinant IFN 16 Recombinant IL 16 Recombinant insulin 12 Recombinant protein 189... [Pg.1877]

Controlled release of human vascular endothelial growth factor (VEGF) or basic fibroblast growth factor (bFGF) from hydrogels composed of thiol-modified... [Pg.339]

Kishimoto, J. Ehama, R. Ge, Y. Kobayashi, T. Nishiyama, T. Detmar, M. Burgeson, R. E. In vivo detection of human vascular endothelial growth factor promoter activity in transgenic mouse skin. Am. J. Pathol. 2000, 257(1), 103-110. [Pg.428]

Abrahams JM, Forman MS, Grady MS, Diamond SL (2001a) Delivery of human vascular endothelial growth factor with platinum coils enhances wall thickening and coil impregnation in a rat aneurysm model. AJNR Am J Neu-roradiol 22 1410-1417... [Pg.270]

Asano, M., Yukita, A., Matsumoto, T., Kondo, S., and Suzuki, H., 1995, Inhibition of tumor growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor. Cancer Res. 55 5296-... [Pg.46]

Kimura H, Weisz A, Kurashima Y, Hashimoto K, Ogura T, D Acquisto F, Addeo R, Makuuchi M, Esumi H. H q)oxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation hy nitric oxide control of hypoxia-inducihle factor-1 activity hy nitric oxide. Blood 2000 95 189-197. [Pg.108]

Sanchez-Elsner T, Botella LM, Velasco B, Corbi A, Attisano L, Bemabeu C. Synergistic cooperation between hypoxia and transforming growth factor- pathways on human vascular endothelial growth factor gene expression. J Biol Chem 2001 276 38527-38535. [Pg.108]

Henry, T. D., Rocha-Singh, K., Isner, J. M., Kereiakes, D. J., Giordano, F. J., Simons, M., Losordo, D. W., Hendel, R. C., Bonow, R. O., Eppler, S. M., Zioncheck, T. F., Holmgren, E. B., and Mccluskey, E. R. 2001. Intracoronary administration of recombinant human vascular endothelial growth factor to patients with coronary artery disease. American Heart Journal, 142, 872-880. [Pg.366]

Guan, Y., L. Ou, G. Hu et al. 2008. Tissue engineering of urethra using human vascular endothelial growth factor gene-modified bladder urothehal cells. Artif Organs 32 91-99. [Pg.683]

See other pages where Human vascular endothelial growth factor is mentioned: [Pg.335]    [Pg.644]    [Pg.428]    [Pg.29]    [Pg.35]    [Pg.296]    [Pg.277]    [Pg.301]    [Pg.368]    [Pg.402]    [Pg.257]    [Pg.258]    [Pg.20]    [Pg.893]    [Pg.919]    [Pg.923]    [Pg.1878]    [Pg.156]    [Pg.122]    [Pg.462]    [Pg.102]    [Pg.381]    [Pg.386]    [Pg.169]   
See also in sourсe #XX -- [ Pg.644 ]



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Anti-human vascular endothelial growth factor

Endothelial

Endothelial growth factors

Endothelialization

Growth factors human

Human vascular endothelial growth

Vascular endothelial growth

Vascular growth

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