Human trials long-term implantation

On the other hand, the internal use of nanoceUulose (e.g., as implants for the vascular system or as carriers for dmg delivery into the bloodstream, etc.), can be dangerous for the human organism, which does not contain cellulolytic enzymes. It can be expected that introduction of alien stable nanoparticles or nanofibrils into internal body systems can cause a thrombus, tumor, or inflammatory or toxic responses. Although some tests on animals gave promising results, the internal use of nanocellulose for the treatment of humans requires further long-term clinical trials. 

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