Human physical mapping

Physical map with over 15.000 STS markers published. See http //wMw.ontl.gPv/hxmix/pukhcat/hxnA-7n5/05detail.hrml Human Genome News, 7i5) (January - March 1996) Detailed Human Physical Map Published by Whiteliead-MIT. ... 

Radiation hybrid mapping Now the most rapid method of localizing a gene or DNA fragment to a subregion of a human chromosome and constructing a physical map. 

Yu, A., et al., "Comparison of Human Genetic and Sequence-Based Physical Maps," Nature, 409, 951-953 (2001). 

The National Academy of Sciences il. S.i endorsed a massive national effort to map and sequence the human genome The project target—to produce genetic and physical maps of increasing resolution, with a fully detailed map of the chromosomes—the project to he completed within a decade and ai a cost estimated to be S3 billion,... 

The physical mapping and sequencing of the mouse VH locus is much less advanced than that of the human. Current estimates of the number of mouse VH... 

Hofker, M.H., Walter, M.A., Cox, D.W. (1989). Complete physical map of the human heavy chain constant region gene complex. Proc. Natl. Acad. Sci. USA 86,5567-5571. 

Matsuda, F., Shin, E.K., Nagaoka, H., Matsumura, R., Haino, M., Fukita, Y., Taka-ishi, S., Imai, T., Riley, J.H., Anand, R., Soeda, E., Honjo, T. (1993). Structure and physical map of 64 variable segments in the 3 0.8-megabase region of the human immunoglobulin heavy-chain locus. Nature Genet. 3, 88-94. 

Hurle B, Lane K, Kenney J, Tarantino LM, Bucan M, Brownstein BH, Ornitz M. 2001. Physical mapping of the mouse tilted locus identifies an association between human deafness loci dfna6/14 and vestibular system development. Genomics 77 189-99. 

Niesler B, Frank B, Kapeller J, Rappold GA (2003) Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E. Gene 310 101... 

O, Dixon K, Stone NE, Cox DR, Haussler D, Kent WJ, Furey T, Rogic S, Kennedy S, Jones S, Rosenthal A, Wen G, Schilhabel M, Gloeckner G, Nyakatura G, Siebert R, Schlegelberger B, Korenberg J, Chen XN, Fujiyama A, Hattori M, Toyoda A, Yada T, Park HS, Sakaki Y, Shimizu N, Asakawa S, et al. A physical map of the human genome. Nature 2001 409(6822) 934-41. 

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