HTS techniques

Figure 15 shows the variation of diamond deposition rates by various activated CVD techniques as well as the HP—HT technique (165). It can be seen that the highest growth rate of activated CVD diamond synthesis is stiU an order of magnitude lower than the HP—HT technique. However, CVD has the potential to become an alternative for diamond growth ia view of the significantly lower cost of activated CVD equipmeat and lower miming and maintenance costs. 

Fig. 15. Variation of diamond deposition rates by various activated CVD techniques as well as the HP—HT technique (165).

MW-HT techniques can shorten the reaction time. For example, Ivanov et al. [38] synthesized ZnO nanocrystals in 10 min with the assistance of microwave hydro-thermal methods. Huang et al. [39] also demonstrated the use of microwave radiation in the hydrothermal synthesis of ZnO complex nanostructures. These nanocrystals showed high photocatalytic activity in a model reaction of Methyl Orange photodegradation. Li et al. [40] synthesized W03 nanorods in 20 min and showed high... 

Reach target physicochemical profile HT physicochemical profiling and virtual screening Limited relevance of some HT techniques dubious predictive capacity of some statistical models... 

Netzer, R., Bischoff, U., and Ebneth, A., HTS techniques to investigate the potential effects of compounds on cardiac ion channels at early-stages of drug discovery, Curr. Opin. Drug Discov. Dev., 6, 462-469, 2003. 

In the same way as for the y-Si3N4 phase, the new spinel structure of Ge3N4 (and of the analogous Sn3N4) has been synthesized with the HP-HT technique... 

HP-HT techniques have been used to synthesize and recover metastable forms of carbon nitrides. A mixmre of Ceo and N2, laser-heated up to 2000-2500 K at about 30 GPa, gives rise to a chemical reaction, visually indicated by... 

In the synthesis of a compound library of allosteric Akt kinase inhibitors 39, Lindsley and coworkers employed different HTS techniques (Scheme 24) [54]. A polymer-supported base and a fluorous thiol scavenger were used in the alkylation reaction of 40. F-SPE purified intermediate was then used for microwave-assisted cycloaddition of 41. Similar intermediates have been used for generation of an unnatural canthine alkaloid library 42 by performing cycloaddition reactions with an indo-tethered acyl hy-drazide [55]. 

High Throughput Screening (HTS) Techniques Overview of Applications in Chemical Biology... 

Chemical Libraries Screening for Biologically Active Small Molecules High Throughput Screening (HTS) Techniques Overview of Proteins, Chemistry and Chemical Reactivity of Synthetic Peptides and Proteins to Elucidate Biological Function... 

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