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Hosts for Heterologous Production of Natural Products

The second system is composed of the RolR regulator and the PAS promoter fused with the operator (rolO) from the Corynebacterium glutamicum resorcinol catabolic operon. This promoter has the low basal level of transcription and can be induced by resorcinol. In summary, there are significant numbers of well-characterized synthetic and inducible promoters to control the expression of gene and gene clusters in streptomycetes [81]. [Pg.495]

Further control of gene expression is performed on the translational level. [Pg.495]

At present, several Streptomyces strains have been utilized as hosts for the production of natural products. Baltz performed an excellent comparative analysis of different Streptomyces hosts for heterologous production [7, 88]. The most widely used strains are S. coelicolor, S. avermitilis, and S. albus]l(y7A [89]. [Pg.496]

Gohain, A., Gogoi, A, Dd nath, R, Yadav, A. et al. (2015) Antimicrobial biosynthetic potential and genetic diversity of endophytic actinomycetes associated with medicinal plants. FEMS Micrd ioL Lett., 362 (19). [Pg.499]

Diaz Diaz, C., Djieto-Lordon, C. et al. (2015) Characterization of actinobacteria associated with three ant-plant mutualisms. Microh. EcoL, 69 (1), 192—203. Wardecld, X., Brotz, E, de Ford, C, von Loewenich, F.D. et al. (2015) Endophytic Streptomyces in the traditional medicinal plant Arnica montana E. secondary metabolites and biological activity. Antonie Van Leeuwenhoek, 108 (2), 391-402. [Pg.499]

Galm, U. and Shen, B. (2006) Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis. Expert Opinion on Drug Discovery, 1, 409. [Pg.257]

See other pages where Hosts for Heterologous Production of Natural Products is mentioned: [Pg.80]    [Pg.495]    [Pg.495]    [Pg.495]    [Pg.497]    [Pg.1824]    [Pg.80]    [Pg.314]    [Pg.470]    [Pg.495]    [Pg.495]    [Pg.495]    [Pg.497]    [Pg.256]    [Pg.216]    [Pg.497]    [Pg.143]    [Pg.313]    [Pg.448]    [Pg.408]    [Pg.36]    [Pg.26]    [Pg.34]    [Pg.6]    [Pg.123]    [Pg.404]    [Pg.525]    [Pg.526]    [Pg.255]    [Pg.143]    [Pg.228]    [Pg.634]    [Pg.61]    [Pg.249]    [Pg.88]    [Pg.113]    [Pg.318]    [Pg.457]    [Pg.459]    [Pg.459]    [Pg.316]    [Pg.1824]    [Pg.2043]    [Pg.472]    [Pg.491]    [Pg.496]    [Pg.496]    [Pg.499]    [Pg.513]    [Pg.398]    [Pg.524]    [Pg.434]    [Pg.20]   


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Heterologous production

Of natural products

Products of nature

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