Host-guest reactions

The most extensive study in the field of host-guest reactions in clathrates has been that of Lahav, Leiserowitz, and co-workers (56,241,243) on the choleic acids. The results of these combined chemical and crystallographic investigations are of possible importance for stereoselective steroid functionalization. In these studies potentially reactive guests were activated thermally or photochemically to produce species that attacked the walls of the channel at specific sites determined by the proximity, orientation, and reactivity of the host molecules at the wall relative to the activated guest species. 

A term used to refer to any chemical process whose rate depends upon saturation of a binding site. Rate saturation is observed in enzyme kinetics, metabolic transport, host-guest reactions, and even heterogenous catalysis such as hydrogenation on metallic surfaces of platinum and nickel. 

Solution We are observing the dynamics of a complexa-tion (host-guest) reaction between DMP and (donated... 

The examples of reactions between guest molecules discussed above demonstrate that inclusion of guest molecules within solid host structures can be exploited as a means of altering their reactivity in comparison to that in dispersed phases. This section presents examples of solid inclusion compounds that undergo reactions involving the molecules of the host structure (either host-guest reactions or chemical transformations of the host molecules). 

The results discussed above highlight the fact that topochemical host-guest reactions in solid inclusion compounds are sensitive to the size and shape of the inclusion cavities and the relative orientations of the host and guest molecules within the crystal structure. Furthermore, these examples demonstrate that reactions in solid inclusion compounds can be associated with high selectivities that are difficult to achieve with conventional synthetic methods in the solution state. 

Host-guest reactions involving thienothiophene hosts... 

The high fluorescence emission of pyrene makes it a useful fluorescence probe to study multistepped host-guest reactions (in the previous example 1 1 and 2 1 additions), by time-resolved fluorescence, steady-state fluorescence, and fluorescence kinetic studies. 

Host-Guest Reactions in Pillared-Layer MOFs. 133... 

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